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Table 1 Associations of antenatal surrogate markers of disease progression of 58 pregnant women (chronic HIV-1 infections) with presence or absence of gag proteins reactivities

From: Human Immunodeficiency Virus (HIV) types Western blot (WB) band profiles as potential surrogate markers of HIV disease progression and predictors of vertical transmission in a cohort of infected but antiretroviral therapy naïve pregnant women in Harare, Zimbabwe

Antenatal variable

HIV-1 WB gag antigen band reactivity

 

Band

P17

P39

P55

Lymphadenopathy Number/Total (%)

Present

4/51 (8%)

0/32 (0%)

2/38 (5%)

 

Absent

0/2 (0%)

4/21 (19%)

3/15 (13%)

 

p-value

0.680

0.010

0.316

Hemoglobin Mean (SD)

Present

10.8 (1.3) N = 54

11.0 (1.2); N = 33

10.9 (1.4); N = 39

 

Absent

11.7 (1.0) N = 2

10.4 (1.5); N = 23

10.6 (1.0); N = 17

 

p-Value

0.312

0.025

0.395

Viral load log 10 Mean (SD)

Present

3.3(1.0); N = 56

3.0 (0.8); N = 35

3.1 (0.9); N = 41

 

Absent

2.3 (0); N = 2

3.7 (1.2); N = 23

3.6 (1.2); N = 17

 

P-value

0.167

0.016

0.072

Vertical Transmission

Present

29/56 (52%)

15/36 (42%)

20/41 (49%)

Number/Total (%)

Absent

0/2 (0%)

14/22 (64%)

9/17 (53%)

 

P-value

0.150

0.104

0.773