From: Human rhinovirus infection in young African children with acute wheezing
HRV-positive n = 128 (58.2%) | HRV-negative n = 92 (41.8%) | OR (95% CI) | ρ-value | |
---|---|---|---|---|
Age (months) (median & IQR) | 13.3(6.0-28.2) | 11.7(6.7-24.6) | 1.00(0.99-1.02) | 0.68 |
Male n (%) | 76 (59) | 52 (41) | 0.89(0.52-1.53) | 0.67 |
Clinical symptoms n (%) | ||||
Cough | 114 (89) | 83 (90) | 1.13(0.47-2.74) | 0.78 |
Wheeze | 108 (84) | 79 (86) | 1.13(0.53-2.40) | 0.76 |
Breathing difficulty | 68 (53) | 43 (47) | 0.77(0.45-1.32) | 0.35 |
Rhinorrhea | 86 (67) | 59 (64) | 0.87(0.50-1.53) | 0.64 |
Night waking | 75 (59) | 52 (57) | 0.92(0.53-1.58) | 0.76 |
Fever >37.5C | 43 (34) | 46 (50) | 1.98(1.14-3.42) | 0.02 |
Diarrhoea | 17 (13) | 10 (11) | 0.80(0.35-1.83) | 0.60 |
Vomiting | 51 (40) | 23 (25) | 0.50(0.28-0.91) | 0.02 |
Duration of symptoms (days) (median & IQR) | 3 (2-7) | 4 (2-7) | 0.99(0.96-1.02) | 0.58 |
Previous episodes of wheezing (median & IQR) | 3 (2-6) | 3 (2-10) | 0.98 (0.94-1.02) | 0.27 |
n = 0 (%) | 29 (22.7) | 21 (23) | ||
n = <3 (%) | 40 (31.2) | 22 (24) | 0.98 (0.35-2.79) | 0.97 |
n = ≥3 (%) | 59 (46.1) | 49 (53) | 0.99 (0.94-1.03 | 0.57 |
Hospital admission n (%) | ||||
General ward | 45(35.2) | 26(28.3) | 1.38(0.77-2.46) | 0.28 |
ICU | 3(2.3) | 4(4.4) | 1.90(0.41-8.67) | 0.41 |
Risk factors n (%) | ||||
Premature birth (< 38 weeks gestation) | 16(13) | 19(21) | 0.55(0.37-1.14) | 0.10 |
Smoker in house | 54(45) | 4 (50) | 1.37(0.80-2.35) | 0.25 |
Relative with asthma | 45(35) | 2 (28) | 1.38(0.34-1.11) | 0.11 |