| IgG (n = 80) | IgM (n = 81) |
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Parameter | PS | SA | Mean Ratio of S/Co values (95% CI)b
| PS | SA | Mean Ratio of S/Co values (95% CI)b
|
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% Sensitivityc
| 82.5 | 91.3 | 1.32 (1.24-1.39) | 61.7 | 75.3 | 1.30 (1.23-1.37) |
% Specificityd
| 100 | 100 | - | 100 | 100 | - |
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aAssays were done using polystyrene (PS) microtiter wells or streptavidin (SA) coated microtiter wells. The number of sera analyzed is denoted by n.
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bThis column represents the mean ratio of S/Co values using SA plates to S/Co values using PS plates; the cut-off values were 0.31 and 0.28 for PS and SA, respectively, in the IgG assay, and 0.23 and 0.25, respectively, in the IgM assay. The 95% confidence interval is indicated in parentheses.
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cPercent Sensitivity = (Number of sera that scored positive by our test/Number of sera that scored positive using PanBio ELISAs) × 100
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dPercent Specificity = (Number of sera that scored negative by our test/Number of sera that scored negative using PanBio ELISAs) × 100