Skip to main content

Table 1 Baseline Characteristics of Patients with HCAP and CAPa

From: Healthcare-associated pneumonia among hospitalized patients in a Korean tertiary hospital

Baseline Characteristics HCAP (n = 231) CAP
(n = 296)
P- value
Age (year) 63.5 ± 13.1 65.4 ± 15.7 0.148
Male 162 (70.1) 194 (65.5) 0.264
Female 69 (29.9) 102 (34.5)  
Underlying diseases    
   Diabetes Mellitus 52 (22.5) 59 (19.9) 0.471
   Chronic lung diseaseb 22 (9.5) 56 (18.9) 0.003
   Central nervous system disorders 26 (11.3) 47 (15.9) 0.127
   Renal disease 31 (13.4) 27 (9.1) 0.118
   Hypertension 93 (40.3) 125 (42.2) 0.649
   Cardiovascular disease 19 (8.2) 62 (20.9) <0.001
   Liver disease 12 (5.2) 16 (5.4) 0.915
   Rheumatologic disease 9 (3.9) 18 (6.1) 0.259
   Malignancy 156 (67.5) 58 (19.6) <0.001
Solid organ malignancy 133 (57.6) 42 (14.2) <0.001
Hematologic malignancy 26 (11.3) 17 (5.7) 0.022
Clinical parameters    
   Confusion 35 (15.2) 34 (11.5) 0.216
   Septic shock at onset 57 (24.7) 46 (15.5) 0.009
   PaO2 < 60 mmHg, SpO2 < 90%, or PaO2/FiO2 < 300 79 (34.2) 96 (32.4) 0.669
   Pleural effusion 43 (18.6) 49 (16.6) 0.536
   Acute renal failure at onset 32 (13.9) 37 (12.5) 0.648
Laboratory findings    
   pH < 7.35 10 (4.3) 23 (7.8) 0.106
   Hematocrit < 30% 87 (37.7) 51 (17.2) <0.001
   Glucose > 250 mg/dL 20 (8.7) 21 (7.1) 0.506
   Blood urea nitrogen > 30 mg/dL 67 (29.0) 49 (16.6) 0.001
   Leukocytes (×103/μl) 12790 ± 13603 13175 ± 7519 0.700
   C-reactive protein (mg/dL) 15.4 ± 11.2 13.1 ± 10.0 0.017
   Erythrocyte Sedimentation Rate (mm) 83.2 ± 33.8 71.4 ± 35.7 <0.001
Eastern Cooperative Oncology
Group (ECOG)
1.7 ± 0.9 1.2 ± 0.9 <0.001
Prior antibiotics use 97 (42.0) 6 (1.0) <0.001
Immunosuppressedc 142 (61.5) 39 (13.2) <0.001
Pneumonia Severity Index Risk Classes 113.7 ± 32.3 92.2 ± 33.6 <0.001
   Low (I-III) 55 (23.8) 159 (53.7)  
   Intermediate (IV) 115 (49.8) 99 (33.4) <0.001
   High (V) 61 (26.4) 38 (12.8)  
  1. a Data are presented as numbers (percentages) unless otherwise indicated. Plus-minus values are means ± standard deviation.
  2. b Chronic lung disease includes asthma, COPD, and structural lung diseases, such as bronchiectasis and interstitial lung disease
  3. c Immunosuppression includes the following: (1) daily administration of systemic corticosteroids (at least 15 mg of prednisone per day for more than one month or combination therapy with low dose corticosteroids and other immunosuppressants including azathioprine, mycophenolate, methotrexate, cyclosporine, or cyclophosphamide); (2) seropositivity for human immunodeficiency virus; (3) received either a solid organ transplant or bone marrow transplant; (4) treated with radiation therapy or chemotherapy for an underlying malignancy during the 6 months prior to hospital admission; (5) an underlying acquired immune deficiency disorder
  4. HCAP healthcare-associated pneumonia
  5. CAP community-acquired pneumonia