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Table 4 Relative quantities of Dicer mRNA in 17 infants with mild and 20 infants with severe RSV disease, compared to 16 controls

From: Reduced Dicer expression in the cord blood of infants admitted with severe respiratory syncytial virus disease

 

RELATIVE QUANTITY (95% CI)

Sig.

Mild RSV disease

0.89

(0.67 - 1.23)

p = 0.481

Severe RSV disease

0.69

(0.56 - 0.87)

p = 0.0021

  1. Note: The median difference and confidence intervals between patient and control groups was calculated using the Hodges-Lehmann estimator for ΔΔCt values, and a 2-ΔΔCt transformation to generate relative quantities. Statistical analysis was done using the Mann-Whitney test. There was significant downregulation of Dicer in the severe RSV group but not in the mild RSV group.
  2. 1Mann-Whitney test