Skip to main content

Table 4 Group comparison of laboratory data

From: Prognostic factors and monomicrobial necrotizing fasciitis: gram-positive versus gram-negative pathogens

Laboratory data Gram positive pathogen (n = 11) Gram Negative pathogen (n = 35) p-value
Total WBC    
   Leukocytosis(> = 12,000/ul) 8 (72.7) 23 (65.7) 1.000
   Leukopenia(< = 4,000/ul) 0 4 (11.4) 0.559
   Leukocytosis or leukopenia 8 (72.7) 27 (77.1) 1.000
Differential count    
   Band formation 9 (81.8) 33 (94.3) 0.238
   Band 10% 3 (27.3) 16 (45.7) 0.320
   neutrophilia(> 7,500/ul) 8 (72.7) 25 (71.4) 1.000
   Lymphocytopenia(< 1,000/ul) 2 (18.2) 19 (54.3)* 0.045
Thrombocytopenia(< 150,000/ul) 0 12 (34.3)* 0.044
Bacteremia 7 (63.6) 17 (48.6) 0.497
Hemoglobin(g/dL) 12.4 (10.0, 14.1) 12.6 (7.7, 15.8) 0.690
C-reactive protein (mg/dL) 178.0 (50, 373) 114.0 (24.4, 354) 0.302
Glucose (mg/dL) 265.4 (121, 842) 164.14(91, 436) 0.065
Sodium (meq/L) 132.4 (124, 136) 135.3 (127, 141)* 0.044
Hypoalbuminemia(< 3 g/dL) 6 (54.5) 24 (68.6) 0.477
LRINEC score 6.18 (4, 10) 4.51 (0, 12)* 0.031
  1. Data are presented as median (min, max) or frequency (%)
  2. Chronic liver dysfunction: liver cirrhosis, viral hepatitis (HBV, or HCV)
  3. LRINEC: Laboratory Risk Indicator for Necrotizing Fasciitis
  4. *: The difference is significant (p < 0.05)