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Table 1 Demographic and clinical characteristics of hospitalized subjects with infective endocarditis in 2000-2002, 2003-2005, 2006-2008, and p value of the Chi square test for linear trend across the study periods

From: Increasing incidence and mortality of infective endocarditis: a population-based study through a record-linkage system

  2000-2002 (n = 562) 2003-2005 (n = 601) 2006-2008 (n = 700) p for trend
Age ≥ 65 years 52.31% 63.56% 63.43% < 0.001
Females 39.15% 41.60% 33.00% 0.017
Chronic renal failure 7.30% 7.99% 8.86% 0.309
Cancer 8.90% 11.15% 10.00% 0.563
Diabetes mellitus 16.01% 17.80% 15.29% 0.673
Previous congestive heart failure 12.99% 12.31% 11.43% 0.396
Valve procedures, previous 12 months 6.76% 5.49% 6.29% 0.767
All hospitalizations, previous 3 months 39.15% 41.60% 35.57% 0.159
Charlson index > 0 47.51% 48.92% 47.86% 0.927