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Table 3 Pregnancy outcome by presence or absence of antibodies against Coxiella burnetii

From: Antibodies against Coxiella burnetii and pregnancy outcome during the 2007-2008 Q fever outbreaks in the Netherlands

Outcome

IgG I and IgG II

≥1:64 (n= 12)

IgM II and IgG II

≥1:64 or IgM II ≥1:64 (n= 37)

No antibodies present

(n= 1125)

χ2 test1

 

n

(%)

n

(%)

n

(%)

P-value

Perinatal mortality

No

12

(100%)

37

(100%)

1101

(97.9%)

 

Yes

0

(0%)

0

(0%)

24

(2.1%)

0.151

Apgar score

<7

0

(0%)

1

(2.7%)

22

(2.0%)

 

≥7

12

(100%)

36

(97.3%)

1079

(98.0%)

0.983

Missing

0

 

0

 

24

  

Birth weight

<2500 g

2

(16.7%)

3

(8.1%)

86

(7.8%)

 

≥2500 g

10

(83.3%)

34

(91.9%)

1015

(92.2%)

0.544

Missing

0

 

0

 

24

  

Birth weight by gestational age (<p10)

No

9

(75.0%)

35

(94.6%)

969

(89.0%)

 

Yes

3

(25.0%)

2

(5.4%)

120

(11.0%)

0.858

Missing

0

 

0

 

36

  

Congenital malformations

No

12

(100%)

37

(100%)

1105

(98.2%)

 

Yes

0

(0%)

0

(0%)

20

(1.8%)

0.346

Gestational age

<37 weeks

1

(8.3%)

2

(5.4%)

109

(10.0%)

 

≥37 weeks

11

(91.7%)

35

(94.6%)

987

(90.1%)

0.378

Missing

0

 

0

 

29

  

Any adverse outcome 2

No

8

(66.7%)

32

(86.5%)

854

(75.9%)

 

Yes

4

(33.3%)

5

(13.5%)

271

(24.1%)

0.358

  1. 1Test for differences between antibodies present (columns 2 and 3) and absent (column 4)
  2. 2Any adverse outcome: perinatal death, birth weight <2500 g, birth weight by gestational age <p10, Apgar score <7, or gestational age <37 weeks.