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Table 6 B lymphocyte subsets and B-cell maturation in cord blood studied in the CD45/CD34/CD19/CD22 and sIgM/CD34/CD19/CD10 combinations (median and range)

From: The impact of maternal HIV infection on cord blood lymphocyte subsets and cytokine profile in exposed non-infected newborns

 

Non exposed controls

HIV exposed

HIV exposed drug using mother

p value

% CD19+

3.6

5.2

7.0

0.01

% CD19+CD5+ *

59.5

77.8

67.6

0.007

% CD45lowCD34+CD19+CD22-/+ **

0.73

0.42

1.1

 
 

(0.2 - 3.13)

(0.07 - 1.22)

(0.78 - 1.4)

0.01

% CD45-/+CD34lowCD19+CD22+ ***

2.62

2.94

13.0

 
 

(0.24 - 6.8)

(1.5 - 8.2)

(8.8-19.4)

0.01

% CD45+CD34-CD19+CD22+ ****

96.7

96.7

86.3

 
 

(91 - 99)

(91.6 - 98.4)

(79 - 90)

0.02

%sIgM-CD34+CD19+CD10-/+ **

0.4

0.2

1.5

 
 

(0.10-2.2)

(0.05-0.95)

(0.4-2.7)

0.05

%sIgM+CD34-/+CD19+CD10-/+ ***

2.4

2.2

6.5

 
 

(0.87-7.1)

(0.6-4.5)

(2.1-71)

0.13

%sIgM+CD34-CD19+CD10-/+ ****

97.1

97.3

92.5

 
 

(91.3-98.9)

(94.6-99.3)

(92.0-95.0)

0.05

  1. * percentage of the total CD19+ cells, ** immature cells, ***intermediary and ****mature B-cells