|  | Clinicians' assessment of suspect cases, n = 44* | Laboratory investigation of probable cases, n = 37 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  | Probable, n = 29* | Non-cases, n = 15 | Confirmed, n = 24 | Non-cases, n = 13* | ||||||||
 | Criteria | + | - | Se.# | + | - | Sp.§ | + | - | Se.# | + | - | Sp.§ |
 | prior contact | 28 | 1 | 97% | 12 | 3 | 20% | 24 | 0 | 100% | 10 | 3 | 23% |
 | fever | 25 | 3 | 89% | 13 | 2 | 13% | 21 | 3 | 88% | 11 | 1 | 8% |
General signs: | headache | 20 | 8 | 71% | 9 | 6 | 40% | 17 | 7 | 71% | 8 | 4 | 33% |
 | nausea/vomiting | 11 | 17 | 39% | 6 | 9 | 60% | 10 | 14 | 42% | 5 | 7 | 58% |
 | loss of appetite | 22 | 6 | 79% | 9 | 6 | 40% | 21 | 3 | 88% | 6 | 6 | 50% |
 | diarrhoea | 11 | 17 | 39% | 3 | 12 | 80% | 11 | 13 | 46% | 2 | 10 | 83% |
 | intense fatigue | 19 | 9 | 68% | 9 | 6 | 40% | 18 | 6 | 75% | 7 | 5 | 42% |
 | abdominal pain | 17 | 11 | 61% | 6 | 9 | 60% | 15 | 9 | 63% | 6 | 6 | 50% |
 | muscle or joint pain | 13 | 15 | 46% | 7 | 8 | 53% | 13 | 11 | 54% | 4 | 8 | 67% |
 | difficulty with swallowing | 7 | 21 | 25% | 1 | 14 | 93% | 7 | 17 | 29% | 1 | 11 | 92% |
 | difficulty with breathing | 5 | 23 | 18% | 0 | 15 | 100% | 5 | 19 | 21% | 0 | 12 | 100% |
 | hiccup | 1 | 27 | 4% | 1 | 14 | 93% | 0 | 24 | 0% | 2 | 10 | 83% |
Bleeding signs: | bleeding gums | 1 | 27 | 4% | 0 | 15 | 100% | 1 | 23 | 4% | 0 | 12 | 100% |
 | bleeding into the eyes | 0 | 28 | 0% | 0 | 15 | 100% | 0 | 24 | 0% | 0 | 12 | 100% |
 | bleeding into the skin | 0 | 28 | 0% | 0 | 15 | 100% | 0 | 24 | 0% | 0 | 12 | 100% |
 | black or bloody stool | 1 | 27 | 4% | 1 | 14 | 93% | 0 | 24 | 0% | 2 | 10 | 83% |
 | bloody vomit | 0 | 28 | 0% | 3 | 12 | 80% | 0 | 24 | 0% | 1 | 11 | 92% |
 | nose bleed | 1 | 28 | 3% | 0 | 15 | 100% | 0 | 24 | 0% | 1 | 12 | 92% |
Case definitions: | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
S1 | contact plus fever | 25 | 3 | 89% | 11 | 4 | 27% | 21 | 3 | 88% | 10 | 2 | 17% |
S2 | at least three general symptoms plus fever | 21 | 7 | 75% | 7 | 8 | 53% | 19 | 5 | 79% | 5 | 7 | 58% |
S3 | any bleeding sign | 3 | 26 | 10% | 4 | 11 | 73% | 1 | 23 | 4% | 4 | 9 | 69% |
S2 or S3 | any clinical case definition | 21 | 7 | 75% | 9 | 6 | 40% | 19 | 5 | 79% | 6 | 6 | 50% |
S = S1 or S2 or S3: | any suspect case definition | 25 | 3 | 89% | 14 | 1 | 7% | 21 | 3 | 88% | 12 | 0 | 0% |
P = S1 or S2 or S3 plus clin.ass. | probable = any suspect case definition plus clinical assessment | Â | Â | Â | Â | Â | Â | 24 | 0 | 100% | 5 | 8 | 62% |
Alternative case def.: $ | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
S1a | contact plus (fever or 3+ general symptoms) | Â | Â | Â | Â | Â | Â | 24 | 0 | 100% | 10 | 2 | 17% |
S2a | fever plus 2+ general symptoms | Â | Â | Â | Â | Â | Â | 21 | 3 | 88% | 9 | 3 | 25% |
S2b | 3+ general symptoms | Â | Â | Â | Â | Â | Â | 22 | 2 | 92% | 6 | 6 | 50% |
S2c | 2+ general symptoms | Â | Â | Â | Â | Â | Â | 24 | 0 | 100% | 10 | 2 | 17% |