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Table 2 Symptoms in suspect EHF cases by result of clinician's assessment, and in probable EHF cases by result of laboratory investigation

From: Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learned

  

Clinicians' assessment of suspect cases, n = 44*

Laboratory investigation of probable cases, n = 37

  

Probable, n = 29*

Non-cases, n = 15

Confirmed, n = 24

Non-cases, n = 13*

 

Criteria

+

-

Se.#

+

-

Sp.§

+

-

Se.#

+

-

Sp.§

 

prior contact

28

1

97%

12

3

20%

24

0

100%

10

3

23%

 

fever

25

3

89%

13

2

13%

21

3

88%

11

1

8%

General signs:

headache

20

8

71%

9

6

40%

17

7

71%

8

4

33%

 

nausea/vomiting

11

17

39%

6

9

60%

10

14

42%

5

7

58%

 

loss of appetite

22

6

79%

9

6

40%

21

3

88%

6

6

50%

 

diarrhoea

11

17

39%

3

12

80%

11

13

46%

2

10

83%

 

intense fatigue

19

9

68%

9

6

40%

18

6

75%

7

5

42%

 

abdominal pain

17

11

61%

6

9

60%

15

9

63%

6

6

50%

 

muscle or joint pain

13

15

46%

7

8

53%

13

11

54%

4

8

67%

 

difficulty with swallowing

7

21

25%

1

14

93%

7

17

29%

1

11

92%

 

difficulty with breathing

5

23

18%

0

15

100%

5

19

21%

0

12

100%

 

hiccup

1

27

4%

1

14

93%

0

24

0%

2

10

83%

Bleeding signs:

bleeding gums

1

27

4%

0

15

100%

1

23

4%

0

12

100%

 

bleeding into the eyes

0

28

0%

0

15

100%

0

24

0%

0

12

100%

 

bleeding into the skin

0

28

0%

0

15

100%

0

24

0%

0

12

100%

 

black or bloody stool

1

27

4%

1

14

93%

0

24

0%

2

10

83%

 

bloody vomit

0

28

0%

3

12

80%

0

24

0%

1

11

92%

 

nose bleed

1

28

3%

0

15

100%

0

24

0%

1

12

92%

Case definitions:

             

S1

contact plus fever

25

3

89%

11

4

27%

21

3

88%

10

2

17%

S2

at least three general symptoms plus fever

21

7

75%

7

8

53%

19

5

79%

5

7

58%

S3

any bleeding sign

3

26

10%

4

11

73%

1

23

4%

4

9

69%

S2 or S3

any clinical case definition

21

7

75%

9

6

40%

19

5

79%

6

6

50%

S = S1 or S2 or S3:

any suspect case definition

25

3

89%

14

1

7%

21

3

88%

12

0

0%

P = S1 or S2 or S3 plus clin.ass.

probable = any suspect case definition

plus clinical assessment

      

24

0

100%

5

8

62%

Alternative case def.: $

             

S1a

contact plus (fever or 3+ general symptoms)

      

24

0

100%

10

2

17%

S2a

fever plus 2+ general symptoms

      

21

3

88%

9

3

25%

S2b

3+ general symptoms

      

22

2

92%

6

6

50%

S2c

2+ general symptoms

      

24

0

100%

10

2

17%

  1. *: n < 29 due to missing clinical data for index case. #: Sensitivity. §: Specificity. $: Alternative case definitions, not used during outbreak