Skip to main content

Advertisement

Table 2 Symptoms in suspect EHF cases by result of clinician's assessment, and in probable EHF cases by result of laboratory investigation

From: Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learned

   Clinicians' assessment of suspect cases, n = 44* Laboratory investigation of probable cases, n = 37
   Probable, n = 29* Non-cases, n = 15 Confirmed, n = 24 Non-cases, n = 13*
  Criteria + - Se.# + - Sp.§ + - Se.# + - Sp.§
  prior contact 28 1 97% 12 3 20% 24 0 100% 10 3 23%
  fever 25 3 89% 13 2 13% 21 3 88% 11 1 8%
General signs: headache 20 8 71% 9 6 40% 17 7 71% 8 4 33%
  nausea/vomiting 11 17 39% 6 9 60% 10 14 42% 5 7 58%
  loss of appetite 22 6 79% 9 6 40% 21 3 88% 6 6 50%
  diarrhoea 11 17 39% 3 12 80% 11 13 46% 2 10 83%
  intense fatigue 19 9 68% 9 6 40% 18 6 75% 7 5 42%
  abdominal pain 17 11 61% 6 9 60% 15 9 63% 6 6 50%
  muscle or joint pain 13 15 46% 7 8 53% 13 11 54% 4 8 67%
  difficulty with swallowing 7 21 25% 1 14 93% 7 17 29% 1 11 92%
  difficulty with breathing 5 23 18% 0 15 100% 5 19 21% 0 12 100%
  hiccup 1 27 4% 1 14 93% 0 24 0% 2 10 83%
Bleeding signs: bleeding gums 1 27 4% 0 15 100% 1 23 4% 0 12 100%
  bleeding into the eyes 0 28 0% 0 15 100% 0 24 0% 0 12 100%
  bleeding into the skin 0 28 0% 0 15 100% 0 24 0% 0 12 100%
  black or bloody stool 1 27 4% 1 14 93% 0 24 0% 2 10 83%
  bloody vomit 0 28 0% 3 12 80% 0 24 0% 1 11 92%
  nose bleed 1 28 3% 0 15 100% 0 24 0% 1 12 92%
Case definitions:              
S1 contact plus fever 25 3 89% 11 4 27% 21 3 88% 10 2 17%
S2 at least three general symptoms plus fever 21 7 75% 7 8 53% 19 5 79% 5 7 58%
S3 any bleeding sign 3 26 10% 4 11 73% 1 23 4% 4 9 69%
S2 or S3 any clinical case definition 21 7 75% 9 6 40% 19 5 79% 6 6 50%
S = S1 or S2 or S3: any suspect case definition 25 3 89% 14 1 7% 21 3 88% 12 0 0%
P = S1 or S2 or S3 plus clin.ass. probable = any suspect case definition
plus clinical assessment
       24 0 100% 5 8 62%
Alternative case def.: $              
S1a contact plus (fever or 3+ general symptoms)        24 0 100% 10 2 17%
S2a fever plus 2+ general symptoms        21 3 88% 9 3 25%
S2b 3+ general symptoms        22 2 92% 6 6 50%
S2c 2+ general symptoms        24 0 100% 10 2 17%
  1. *: n < 29 due to missing clinical data for index case. #: Sensitivity. §: Specificity. $: Alternative case definitions, not used during outbreak