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Table 1 Univariate analysis of the risk factors for defaulting from TB treatment among HIV subjects in the State of Pernambuco, 2007-2009

From: Risk factors for default from tuberculosis treatment in HIV-infected individuals in the state of Pernambuco, Brazil: a prospective cohort study

VARIABLES Default Treatment success OR 95% CI P-value
  n % n %    
BIOLOGICAL        
Sex        
Female 15 17.6 57 30.3 1.00 - -
Male 70 82.3 131 69.7 2.03 1.07 - 3.84 0.030
Age group        
   18 to 29 years 33 38.8 35 18.6 1.00 - -
   30 to 49 years 48 56.5 131 69.7 0.38 0.21 - 0.69 0.001
   50 years or more 4 4.7 22 11.7 0.19 0.06 - 0.61 0.006
Race        
White 15 17.6 42 22.3 1.00 - -
Non-white 70 82.3 146 77.7 1.34 0.69 - 2.58 0.378
SOCIOECONOMIC        
City of Residence        
Recife 39 45.9 78 41.5 1.00 - -
Metropolitan Region 35 41.2 78 41.5 0.89 0.51 - 1.56 0.702
Inland 11 12.9 32 17.0 0.68 0.31 - 1.50 0.350
Marital status        
Married 12 14.1 54 28.7 1.00 -  
Single/Separated/Widowed 73 85.9 134 71.3 2.45 1.23 - 4.87 0.011
Shared residence        
Family/Partner 17 20.0 33 17.6 1.00   
Alone 68 80.0 155 82.4 1.74 0.61 - 2.25 0.629
Education level        
Complete or incomplete primary education 69 81.2 128 69.1 1.00 - -
Complete or incomplete secondary or university education 16 21.0 60 31.9 0.49 0.26 - 0.92 0.027
Employment        
Yes 17 20.0 34 18.1 1.00 - -
No 68 80.0 154 81.9 0.88 0.46 - 1.68 0.707
Income*        
< 1 minimum wage 65 22.6 117 37.4 1.00 - -
≥ 1 minimum wage 19 77.4 70 62.6 0.48 0.27 - 0.88 0.017
HABITS        
Alcohol consumption        
None or light drinker 69 81.2 177 94.1 1.00 - -
Moderate or Heavy drinker 16 18.8 11 5.8 3.73 1.64 - 8.44 0.002
Smoking status        
Never smoked 22 25.9 81 43.1 1.00 - -
Former smokers 14 16.5 45 23.9 1.14 0.53 - 2.45 0.727
Current smokers 49 57.6 62 33.0 2.90 1.59 - 5.31 0.001
Illicit drug use        
No 63 74.1 129 68.6 1.00   
Yes 22 25.9 59 31.4 0.76 0.42 - 1.35 0.358
HIV VARIABLES        
Opportunistic Disease        
No 13 15.3 32 17.0 1.00 - -
Yes 72 84.7 156 83.0 1.13 0.56 - 2.29 0.722
AIDS        
No 3 3.5 6 3.2 1.00 -  
Yes 82 96.5 182 97.0 0.90 0.21 - 3.69 0.885
CD4 T-cell count* (cell/mm 3 )        
200 or more 33 42.3 114 62.3 1.00 - -
Less than 200 45 57.7 69 37.7 2.25 1.31 - 3.86 0.003
Beginning of HAART        
Did not start HAART 33 38.8 23 12.23 1.00 - -
Before treatment for TB 42 49.4 96 51.1 0.30 0.16 - 0.58 0.000
Up to second month of TB treatment 8 9.4 41 21.8 0.13 0.05 - 0.34 0.000
After the second month of TB treatment 2 2.3 28 14.9 0.05 0.01 - 0.23 0.000
TB VARIABLES        
Setting of beginning of TB treatment        
Outpatient clinic 33 38.8 88 46.8 1.00 - -
Hospital 52 61.2 100 53.2 1.38 0.82 - 2.33 0.220
TB clinical site        
Pulmonary 57 32.4 119 67.6 1.00 - -
Extra-pulmonary 19 22.3 47 25.0 0.84 0.45 - 1.56 0.591
Disseminated 9 10.6 22 11.7 0.85 0.63 - 1.97 0.369
Type of regimen for TB treatment        
Regimen 1 62 75.9 134 71.3 1.00 - -
Regimen 1R 19 22.3 41 21.8 1.00 0.53 - 1.86 0.996
Other regimens 4 4.7 13 6.9 0.66 0.20 - 2.12 0.491
Adverse effects        
No 76 89.4 171 91.0 1.00 - -
Yes 9 10.6 17 9.0 1.19 0.50 - 2.79 0.687
Previous Treatment        
No 39 45.9 84 44.7 1.00 - -
Yes 46 30.7 104 69.3 0.95 0.56 - 1.59 0.853
  1. OR, odds ratio; CI, confidence interval; HAART, highly active antiretroviral therapy.
  2. *The number of individuals varied because of missing values.