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Table 1 Incidence of gross pathologies

From: Enhanced upper genital tract pathologies by blocking Tim-3 and PD-L1 signaling pathways in mice intravaginally infected with Chlamydia muridarum

Group Total mice No of mice Total oviducts No of oviducts with hydrosalpinx scores
   None Uni Bi   0 1 2 3 4 Total score
Isotype control 10 2 0 8 20 4 2 2 5 7* 49
αTim-3+ αPD-L1 10 0 1 9 20 1 2 0 3 14* 67
  1. *p = 0.028
  2. Mice were sacrificed 60 days after infection and the reproductive tissues were isolated and inspected for gross pathologies (see Figure 2 for images). Number of mice without (none) or with hydrosalpinx on single (Uni) or both (Bi) sides of the reproductive tissues was listed on the left portion of the table. Number of oviducts without (0) or with varying severity degrees (1 to 4) of hydrosalpinx was listed on the right portion of the table. Fisher Exact test was used to compare the differences in incidences of mouse with hydrosalpinx or oviducts with varying degrees of hydrosalpinx between the control and antibody treatment groups. P-vales with statistic differences were marked. * stands for p < 0.05.