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Table 1 Summary of main clinical, laboratory and imaging findings from patient 1

From: Disseminated rhodococcus equi infection in HIV infection despite highly active antiretroviral therapy

Onset of symptoms (date) Presenting symptoms Site of R. equi infection (diagnostic technique) CD 4 + cells, HIV-1 RNA (VL) HAART Treatment Duration
April 2002 fever, cough lung (culture of sputum, chest X-ray). disseminated infection (blood culture) 123 cells/μl, VL < 50 copies/ml didanosine, lamivudine, indinavir induction (i.v.): vancomycin 500 mg q6h imipenem 500 mg q6h ceftriaxone 2 g qd ciprofloxacin 400 mg bid maintanance (p.o.): ciprofloxacin 500 mg bid induction: 8 weeks maintanance:15 weeks
May 2002 seizures head (brain MRI, culture of surgically removed brain abscess)   didanosine, lamivudine,indinavir surgery, antibiotic therapy (see above)  
December 2002 anisocoria, right hemiparesis, hypoaesthesia, hypoallaesthesia, dysmetria CNS (brain MRI) 143 cells/μl, VL < 50 copies/ml didanosine, lamivudine, indinavir i.v.: ciprofloxacin 400 mg tid vancomycin 500 mg q6h ceftriaxone 2 g qd 3 weeks
  1. Notes. VL viral load; i.v. intravenous; p.o. per os; CNS central nervous system; MRI magnetic resonance imaging