Table 2 Outcome of the different treatment groups
Treatment groups | Number of patients with P. aeruginosasusceptible to colistin AND one beta-lactam | Clinical failure when only susceptible to colistin | Clinical failure when susceptible to colistin and at least one other antibiotic agent | Microbiological failure | Favorable clinical response | Mortality |
|---|---|---|---|---|---|---|
Inhalation | 4/6 | 0/2 | 0/4 | 5/5 1 no control data | 6/6 | 0/6 |
Inhalation + Parenteral | 3/9; 1/9 was susceptible to aminoglycosides | 1/5 | 1/4 | 9/9 | 7/9 | 3/9 |
Inhalation and inhalation + parenteral | 8/15 | 1/7 | 1/8 | 14/14 | 13/15 | 3/15 |
Parenteral | 2/5 | 2/3 | 1/2 | 5/5 | 2/5 p = 0.06 as compared to the inhalation group p = 0.27 as compared to the parenteral + inhalation group p = 0.07 as compared to both the inhalation and inhalation + parenteral group | 5/5 p = 0.002 as compared to the inhalation group; p = 0.03 as compared to the parenteral + inhalation group; p = 0.003 as compared to both the inhalation and inhalation + parenteral group |