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Table 2 Outcome of the different treatment groups

From: A retrospective observational study on the efficacy of colistin by inhalation as compared to parenteral administration for the treatment of nosocomial pneumonia associated with multidrug-resistant Pseudomonas aeruginosa

Treatment groups Number of patients with P. aeruginosasusceptible to colistin AND one beta-lactam Clinical failure when only susceptible to colistin Clinical failure when susceptible to colistin and at least one other antibiotic agent Microbiological failure Favorable clinical response Mortality
Inhalation 4/6 0/2 0/4 5/5
1 no control data
6/6 0/6
Inhalation + Parenteral 3/9; 1/9 was susceptible to aminoglycosides 1/5 1/4 9/9 7/9 3/9
Inhalation and inhalation + parenteral 8/15 1/7 1/8 14/14 13/15 3/15
Parenteral 2/5 2/3 1/2 5/5 2/5
p = 0.06 as compared to the inhalation group
p = 0.27 as compared to the parenteral + inhalation group
p = 0.07 as compared to both the inhalation and inhalation + parenteral group
5/5
p = 0.002 as compared to the inhalation group;
p = 0.03 as compared to the parenteral + inhalation group;
p = 0.003 as compared to both the inhalation and inhalation + parenteral group