Table 1 Patient characteristics of the different treatment groups
Inhalation | Parenteral + Inhalation | Parenteral | All patients treated by Inhalation | p-value (difference between groups?) | |
|---|---|---|---|---|---|
Number of patients (medical-surgical) | 6 (1-5) | 9 (5-4) | 5 (3-2) | 15 | / |
Age (years) | 62.5 (15-84) | 67.9 (59-76) | 64.8 (46-77) | 65.7 (15-84) | 0.91 |
Gender (Male %) | 66.7% | 77.8% | 60.0% | 58% | 0.83 |
SOFA-score at admission | 5.2 (2-9) | 6.4 (0-15) | 10.0 (3-13) | 5.9 (2-15) | 0.18 |
SOFA-score start colistin | 6.3 (1-15) | 6.7 (2-11) | 6.0 (3-9) | 6.5 (1-15) | 0.87 |
SAPS3-score | 80.7 (70-88) | 80.8 (70-95) | 79.0 (73-85) | 80.7 (70-95) | 0.92 |
Length of stay (days) | 55.0 (19-103) | 73.0 (16-141) | 40.0 (29-64) | 65.8 (16-141) | 0.16 |
Time between admission and development of the pneumonia (days) | 28.0 (7-75) | 25.1 (8-68) | 19.6 (13-29) | 16.7 (7-75) | 0.99 |
Treatment duration (days) | 27.2 (6-96) | 19.3 (3-46) | 21.0 (9-28) | 22.5 (3-96) | 0.87 |
Creatinine at onset colistin; RRT patients excluded (mg/dL) | 0.8 (0.7-1.2) | 2.3 (0.9-4.7) | 0.9 (0.8-1.0) | 1.6 (0.7-4.7) | 0.39 |
Creatinine during colistin therapy; RRT patients exluded (mg/dL) | 1.0(0.6-1.3) | 2.6 (1.1-5.8) | 1.9 (1.9-2.0) | 1.9 (0.6-5.8) | 0.36 |
Number of RRT patients | 2/6 | 4/9 | 2/5 | 6/15 | / |