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Table 2 Major clinical and laboratory findings in hospitalized children with influenza A/H1N1v infection

From: Pandemic A/H1N1v influenza 2009 in hospitalized children: a multicenter Belgian survey

 

N = 215

 

N = 201¹

Presentation on admission

n (%)

Blood test values on admission

 

H1N1 suspicion

121 (56)

Median Leukocyte count/mm3

9050

  

(IQR*)

(6070-12060)

Symptoms/signs

 

N (%) of patients with leukopenia ≤5000/mm 3

27 (13)

Fever

188 (88)

Median Lymphocyte count/mm3

2147

Cough

129 (60)

(IQR)

(1249-3632)

Rhinorrhea

105 (49)

N (%) of patients with lymphopenia ≤1000/mm 3

33 (16)

Loss of appetite

58 (27)

  

Vomiting

54 (25)

Median PMN** count/mm3

4378

Asthenia

49 (23)

(IQR)

(2667-8179)

Diarrhea

39 (18)

N (%) of patients with neutropenia ≤1500/mm 3

21 (10)

Convulsion

21 (10)

  

Dehydration

11 (5)

Median Platelet count/mm3

297500

Headache

11 (5)

(IQR)

(211000-381500)

Myalgia

10 (5)

N (%) of patients with thrombocytopenia ≤150.10 3 /mm 3

12 (6)

Rash

7 (3)

  

Abdominal pain

5 (2)

Median CRP*** (mg/dL)

1.55

Thoracic pain

5 (2)

(IQR)

(< 0.5-5.15)

  

range

< 0.5-44.7

  

N (%) of patients with CRP > 5 mg/dl

51 (25)

Reason for hospitalization

n (%)

Respiratory complications

n (%)

Altered general status

89 (41)

Hypoxemia2

58 (27)

Respiratory distress

78 (36)

median oxygen saturation 3

90%

(85-92 IQR)

IV treatment

67 (31)

median duration of oxygen supplementation

2.5 days

Underlying disease

53 (25)

Lobar pneumonia

57 (27)

O2 requirement

52 (24)

Diffuse pneumonia

18 (8)

< 3 months old

41 (19)

Pleural effusion

13 (6)

Seizure/malaise

22 (10)

Apnea

3 (1)

Anorexia/vomiting

14 (7)

Pneumothorax

2 (1)

« Sepsis-like » illness

6 (3)

  

Parental request/non compliance

2 (1)

  
  1. Legend: *IQR = interquartile range; **PMN = polymorphonuclear leukocytes; ***CRP = C-reactive protein; 1 201 children with blood results available on admission; 2 defined as Hb oxygen saturation less than 94%; 3 transcutaneous saturation