5 years as compared to those ≤ 5 years are 0.370 (95% CI = 0.1733 - 0.7915, p = 0.010). In contrast, even when ParaCheck Pf® faint bands are considered positive, the odds of misdiagnosis by ParaCheck Pf® for those > 5 years as compared to those ≤ 5 years are 0.837 (95% CI = 0.459 - 1.547, p = 0.5383). Conclusions We provide compelling evidence that in areas of low transmission, "faint bands" should be considered a negative test when used to inform clinical decision-making. Correct interpretation of RDT test bands in a clinical setting plays a central role in successful malaria surveillance, appropriate patient management and most importantly reducing misdiagnosis."/>
Diagnostic Method | Estimated Prevalence |
---|---|
Local Microscopy | 46.4% (95% CI = 40.6%-52.2%) |
ParaCheck Pf®
(If classify faint bands as -) | 1.7% (95% CI = 0.2%-3.2%) |
ParaCheck Pf®
(If classify faint bands as +) | 25.4% (95% CI = 20.4%-30.5%) |
Quality Control Microscopy | 2.1% (95% CI = 0.4%-3.8%) |