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Figure 3 | BMC Infectious Diseases

Figure 3

From: Decrease of virulence for BALB/c mice produced by continuous subculturing of Nocardia brasiliensis

Figure 3

Histological features of BALB/c mice inoculated with N. brasiliensis HUJEG-1 without subculturing. A: After one week fragments of the colonies are seen surrounded by PMNs; 400×. B: At three weeks we can observe well formed grains; 100×. C: Five weeks after infection well formed grains in micro-abscesses (100×) surrounded by a layer of foamy cells are observed (D; 600×). E: At seven weeks there is an abundance of grains present in the lesions arranged in a multilocular form; 100×. F: Biopsy taken after 12 weeks showing grains and giant foamy cells immersed in huge abscesses of necrotic PMNs; 100×. H&E stain.

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