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Table 3 MIC distributions for S. pneumoniae, H. influenza, and M. catharralis included in the study

From: Pharmacodynamic evaluation of commonly prescribed oral antibiotics against respiratory bacterial pathogens

  Percentage (%) of bacteria at each MIC value (mg/L)
Bacterial group (n) and antimicrobial 0.008 0.016 0.032 0.06 0.125 0.25 0.5 1 2 4 8 16 32 > 32
S. pneumoniae (103)               
   Penicillin 2.9 27.2 24.3 18.4 7.8 5.8 1.0 9.7 2.9 0.0 0.0 0.0 0.0 0.0
   Amoxicillin 0.0 1.0 64.1 17.5 2.9 1.9 1.0 1.0 7.8 1.9 1.0 0.0 0.0 0.0
   Co-amoxiclav 0.0 1.0 64.1 17.5 2.9 1.9 1.0 1.0 7.8 1.9 1.0 0.0 0.0 0.0
   Cefaclor 0.0 0.9 0.0 1.9 4.6 36.1 37.0 5.6 1.9 1.9 0.9 0.9 5.6 2.8
   Azithromycin 0.0 0.0 7.8 63.1 20.4 0.0 0.0 0.0 0.0 0.0 1.9 1.0 0.0 5.8
   Levofloxacin 0.0 0.0 0.0 0.0 0.0 0.0 14.6 80.6 4.9 0.0 0.0 0.0 0.0 0.0
   Gatifloxacin 0.0 0.0 0.0 0.0 2.9 79.6 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0
   Moxifloxacin 0.0 0.0 0.0 10.7 71.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
H. influenzae (98)               
   Penicillin 0.0 0.0 0.0 0.0 55.1 16.3 11.2 5.1 0.0 0.0 3.1 4.1 5.1 0.0
   Amoxicillin 0.0 0.0 0.0 0.0 7.1 51.0 19.4 8.2 2.0 3.1 0.0 0.0 9.2 0.0
   Co-amoxiclav 0.0 0.0 0.0 0.0 9.2 44.9 30.6 12.2 3.1 0.0 0.0 0.0 0.0 0.0
   Azithromycin 0.0 0.0 0.0 0.0 3.1 5.1 24.5 44.9 21.4 1.0 0.0 0.0 0.0 0.0
   Levofloxacin 30.6 66.3 2.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
   Gatifloxacin 0.0 96.9 2.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
   Moxifloxacin 11.2 67.3 18.4 2.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
M. catharralis (29)               
   Amoxicillin 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.9 13.8 24.1 27.6 20.7 0.0
   Co-amoxiclav 0.0 0.0 0.0 0.0 51.7 41.4 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0
   Azithromycin 0.0 0.0 0.0 96.6 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
   Levofloxacin 0.0 0.0 93.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
   Gatifloxacin 0.0 20.7 75.9 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
   Moxifloxacin 0.0 0.0 34.5 65.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
  1. MIC = minimum inhibitory concentration; Co-amoxiclav = amoxillin-clavulanate