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Table 3 Distribution of genotypes in cases and controls and their risks with pulmonary tuberculosis

From: Fine mapping of genetic polymorphisms of pulmonary tuberculosis within chromosome 18q11.2 in the Chinese population: a case-control study

  Case Control      Model  
SNP N % N % cOR (95%CI) P aOR (95%CI)a P a Modelb OR(95%CI) P
rs8087945 A > G    
AA 338 60.36 459 61.20 1   1   Dom 1.02(0.80-1.29) 0.885
AG 193 34.46 252 33.60 1.04(0.82-1.31) 0.742 1.04(0.81-1.33) 0.763 Rec 0.88(0.52-1.48) 0.619
GG 29 5.18 39 5.20 1.01(0.61-1.67) 0.970 0.89(0.52-1.51) 0.660 Add 0.99(0.82-1.21) 0.946
rs12456774 A > G    
AA 272 48.66 372 49.60 1   1   Dom 1.01(0.80-1.27) 0.942
AG 239 42.75 307 40.93 1.06(0.85-1.34) 0.594 1.05(0.83-1.34) 0.675 Rec 0.81(0.54-1.21) 0.299
GG 48 8.59 71 9.47 0.92(0.62-1.38) 0.670 0.83(0.55-1.26) 0.376 Add 0.96(0.81-1.15) 0.683
rs12457731 A > G    
AA 524 90.66 691 91.52 1   1   Dom 1.13(0.76-1.69) 0.544
AG 49 8.48 62 8.21 1.04(0.70-1.54) 0.836 1.05(0.70-1.59) 0.811 Rec 3.42(0.65-18.02) 0.148
GG 5 0.86 2 0.27 3.30(0.64-17.05) 0.155 3.43(0.65-18.09) 0.146 Add 1.19(0.82-1.71) 0.36
rs12958098 C > T    
CC 162 28.98 199 26.82 1   1   Dom 0.87(0.68-1.13) 0.299
CT 267 47.76 359 48.38 0.91(0.70-1.19) 0.497 0.88(0.67-1.15) 0.341 Rec 0.94(0.72-1.24) 0.677
TT 130 23.26 184 24.80 0.87(0.64-1.18) 0.364 0.87(0.63-1.20) 0.387 Add 0.93(0.79-1.09) 0.370
rs4800136 A > C    
AA 520 92.36 696 92.06 1   1   Dom 0.94(0.61-1.44) 0.776
AC 42 7.46 59 7.81 0.95(0.63-1.44) 0.818 0.92(0.59-1.42) 0.702 Rec 2.39(0.15-39.23) 0.543
CC 1 0.18 1 0.13 1.34(0.08-21.45) 0.837 2.37(0.14-38.99) 0.546 Add 0.96(0.63-1.45) 0.838
rs4800417 C > T    
CC 366 65.24 503 66.80 1   1   Dom 1.09(0.85-1.38) 0.505
CT 173 30.84 219 29.08 1.09(0.85-1.38) 0.502 1.11(0.86-1.42) 0.434 Rec 0.91(0.50-1.66) 0.763
TT 22 3.92 31 4.12 0.98(0.56-1.71) 0.931 0.94(0.52-1.72) 0.844 Add 1.05(0.85-1.29) 0.646
  1. a: Adjusted for age, sex, education, smoking and drinking
  2. b: Dom, dominant model; Rec, recessive model; Add, additive mode