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Table 3 Distribution of genotypes in cases and controls and their risks with pulmonary tuberculosis

From: Fine mapping of genetic polymorphisms of pulmonary tuberculosis within chromosome 18q11.2 in the Chinese population: a case-control study

 

Case

Control

    

Model

 

SNP

N

%

N

%

cOR (95%CI)

P

aOR (95%CI)a

P a

Modelb

OR(95%CI)

P

rs8087945 A > G

   

AA

338

60.36

459

61.20

1

 

1

 

Dom

1.02(0.80-1.29)

0.885

AG

193

34.46

252

33.60

1.04(0.82-1.31)

0.742

1.04(0.81-1.33)

0.763

Rec

0.88(0.52-1.48)

0.619

GG

29

5.18

39

5.20

1.01(0.61-1.67)

0.970

0.89(0.52-1.51)

0.660

Add

0.99(0.82-1.21)

0.946

rs12456774 A > G

   

AA

272

48.66

372

49.60

1

 

1

 

Dom

1.01(0.80-1.27)

0.942

AG

239

42.75

307

40.93

1.06(0.85-1.34)

0.594

1.05(0.83-1.34)

0.675

Rec

0.81(0.54-1.21)

0.299

GG

48

8.59

71

9.47

0.92(0.62-1.38)

0.670

0.83(0.55-1.26)

0.376

Add

0.96(0.81-1.15)

0.683

rs12457731 A > G

   

AA

524

90.66

691

91.52

1

 

1

 

Dom

1.13(0.76-1.69)

0.544

AG

49

8.48

62

8.21

1.04(0.70-1.54)

0.836

1.05(0.70-1.59)

0.811

Rec

3.42(0.65-18.02)

0.148

GG

5

0.86

2

0.27

3.30(0.64-17.05)

0.155

3.43(0.65-18.09)

0.146

Add

1.19(0.82-1.71)

0.36

rs12958098 C > T

   

CC

162

28.98

199

26.82

1

 

1

 

Dom

0.87(0.68-1.13)

0.299

CT

267

47.76

359

48.38

0.91(0.70-1.19)

0.497

0.88(0.67-1.15)

0.341

Rec

0.94(0.72-1.24)

0.677

TT

130

23.26

184

24.80

0.87(0.64-1.18)

0.364

0.87(0.63-1.20)

0.387

Add

0.93(0.79-1.09)

0.370

rs4800136 A > C

   

AA

520

92.36

696

92.06

1

 

1

 

Dom

0.94(0.61-1.44)

0.776

AC

42

7.46

59

7.81

0.95(0.63-1.44)

0.818

0.92(0.59-1.42)

0.702

Rec

2.39(0.15-39.23)

0.543

CC

1

0.18

1

0.13

1.34(0.08-21.45)

0.837

2.37(0.14-38.99)

0.546

Add

0.96(0.63-1.45)

0.838

rs4800417 C > T

   

CC

366

65.24

503

66.80

1

 

1

 

Dom

1.09(0.85-1.38)

0.505

CT

173

30.84

219

29.08

1.09(0.85-1.38)

0.502

1.11(0.86-1.42)

0.434

Rec

0.91(0.50-1.66)

0.763

TT

22

3.92

31

4.12

0.98(0.56-1.71)

0.931

0.94(0.52-1.72)

0.844

Add

1.05(0.85-1.29)

0.646

  1. a: Adjusted for age, sex, education, smoking and drinking
  2. b: Dom, dominant model; Rec, recessive model; Add, additive mode
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BMC Infectious Diseases

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