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Table 1 Characteristics of studies included in the meta-analysis

From: Pleural fluid soluble triggering receptor expressed on myeloid cells-1 as a marker of bacterial infection: a meta-analysis

STUDY/YEAR

COUNTRY

STUDY POPULATION

AGE

STUDY DESIGN

BLINDING OF INVESTIGATORS

MEANS OF DIAGNOSIS OF BACTERIAL EFFUSIONS

TYPE OF BACTERIAL INFECTION

ASSAY METHOD

Chan et al./2007

Taiwan

ICU/

hospital ward

NR

prospective

NR

clinical and biochemical findings; radiological studies; Gram stain; culture

10 PPE and 12 empyemas

ELISA

Kim et al./2007

Korea

Hospital ward

> 18

prospective

NR

clinical and biochemical findings; radiological studies; culture;response to antibiotic therapy

17 PPE

ELISA

Sim et al./2007

Korea

Hospital ward

NR

prospective

NR

clinical and biochemical findings; radiological studies; culture;response to antibiotic therapy

15 PPE

ELISA

Huang et al./2008

China

Hospital ward

17-81

prospective

NR

clinical and biochemical findings; radiological studies; culture;response to antibiotic therapy

4 PPE and 17 empyemas

ELISA

Bishara et al./2009

Israel

ICU/

hospital ward

NR

prospective

Yes

clinical and biochemical findings; Gram stain; culture

17 empyemas

ELISA

Porcel et al./2009

Spain

ICU/

hospital ward

NR

retrospective

Yes

clinical and biochemical findings; radiological studies; culture;response to antibiotic therapy

128 PPE and 30 empyemas

ELISA

Determann et al./2010

The Netherlands

ICU

NR

prospective

NR

clinical findings; Light's criteria; bacterial culture,response to antibotic therapy

5 PPE and 11 empyemas

ELISA

  1. PPE: Parapneumonic effusions; ELISA: Enzyme linked immunosorbent assay