Table 2 Propensity score adjusted associations between receipt of nafcillin or cefazolin versus vancomycin and 30-day in-hospital mortality
Association | Adjusted hazard ratio and 95% confidence interval | Variables included in the propensity score |
|---|---|---|
Receipt of nafcillin or cefazolin versus vancomycin and 30-day in-hospital mortality | 0.21 (0.09, 0.47) | Severity of illness Aggregate comorbidity Admission to the ICU Age Hemodialysis Endocarditis Time to receipt of appropriate therapy Receipt of other anti -staphylococcal antibiotic |
Switch from vancomycin to nafcillin or cefazolin versus remaining on vancomycin and 30-day in-hospital mortality | 0.31 (0.10, 0.95) | Severity of illness Aggregate comorbidity Admission to the ICU Community-associated infection Hemodialysis Age Endocarditis Time to receipt of appropriate therapy |