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Table 1 Characteristics of the study population stratified by receipt of nafcillin or cefazolin

From: Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia

 

Received only nafcillin or cefazolin

(n = 38)

Received both nafcillin or cefazolin and vancomycin

(n = 135)

Received only vancomycin

(n = 94)

p

Diabetes

5 (13.2%)

7 (5.2%)

13 (14.0%)

0.06

Renal disease

0 (0%)

9 (6.7%)

13 (14.0%)

0.02

Severity of illness score, median, IQR

11.5 (6.0, 16.0)

16.0 (7.0, 25.0)

21.0 (14.0, 29.0)

< 0.01

Charlson Comorbidity Index, median, IQR

0 (0, 2)

1 (0, 3)

2 (1,4)

< 0.01

Endocarditis

9 (23.7%)

28 (20.7%)

3 (3.2%)

< 0.01

Pneumonia

1 (2.6%)

12 (8.9%)

3 (3.2%)

0.13

Osteomyelitis

1 (2.6%)

7 (5.2)

1 (1.1%)

0.22

Wound Infection

3 (7.9%)

4 (3.0%)

2 (2.1%)

0.23

Hemodialysis

0 (0%)

13 (9.6%)

18 (19.2%)

< 0.01

Community-associated infection

26 (68.4%)

94 (69.6%)

54 (57.5%)

0.14

ICU admission before culture collection

6 (15.8%)

40 (29.6%)

28 (29.8%)

0.20

Age, mean ± SD, year

51.0 ± 16.4

48.0 ± 15.6

49.8 ± 16.9

0.78

Female sex

17 (44.7%)

48 (35.6%)

32 (34.0%)

0.49

Presence of central venous catheter

19 (50.0%)

61 (45.2%)

59 (62.8%)

0.03

Central venous catheter removed

8/19 (42.1%)

43/61 (70.5%)

38/59 (64.4%)

0.08

  1. Data are no. (%) of admissions, unless otherwise indicated. IQR, interquartile range; ICU, intensive care unit; SD, standard deviation.