Potential immunomodulatory effects of latent toxoplasmosis in humans

BMC Infectious Diseases

Table 2 Comparison of the flow cytometry data from Toxoplasma-negative and Toxoplasma-positive men and women

	Age P	Sex P	Toxo P	sex-toxo P	women-neg mean	women-pos mean	men-neg mean	men-pos mean
all immunology outpatients N = 440
CD3 (× 10⁶/L)	0.000*	0.009*	0.599	0.164	1549.190	1507.236	1481.540	1190.571
CD19 (× 10⁶/L)	0.000*	0.002*	0.045*	0.012*	254.091	224.514	262.205	155.143
CD4 (× 10⁶/L)	0.000*	0.000*	0.474	0.149	989.026	977.625	878.469	722.786
CD8 (× 10⁶/L)	0.000*	0.395	0.974	0.439	512.725	490.028	527.973	431.429
CD16 + 56 (× 10⁶/L)	0.709	0.861	0.508	0.016*	215.268	243.722	257.795	208.857
CD4/CD8	0.001*	0.021*	0.835	0.875	2.162	2.211	1.809	2.020
patients with allergies, seasonal allergic rhinitis and asthma J.30.1-4, N = 117
CD3 (× 10⁶/L)	0.002*	0.291	0.990	0.920	1566.797	1444.375	1544.031	1331.600
CD19 (× 10⁶/L)	0.000*	0.852	0.723	0.208	223.625	232.063	279.469	205.200
CD4 (× 10⁶/L)	0.026*	0.121	0.621	0.731	979.719	930.875	855.938	839.000
CD8 (× 10⁶/L)	0.074	0.704	0.549	0.856	532.062	443.125	574.125	491.000
CD16 + 56 (× 10⁶/L)	0.180	0.913	0.866	0.032*	223.652	319.500	283.788	236.000
CD4/CD8	0.011*	0.727	0.648	0.400	2.069	2.174	1.661	2.222
patients with immunodeficiencies, D89.9, N = 250
CD3 (× 10⁶/L)	0.000*	0.077	0.423	0.112	1479.986	1509.234	1481.694	1105.000
CD19 (× 10⁶/L)	0.000*	0.141	0.116	0.210	249.216	220.213	251.613	128.143
CD4 (× 10⁶/L)	0.065	0.007*	0.251	0.089	950.075	972.426	884.903	635.000
CD8 (× 10⁶/L)	0.000*	0.829	0.877	0.299	486.552	505.149	534.807	419.429
CD16 + 56 (× 10⁶/L)	0.992	0.875	0.271	0.161	211.745	218.851	250.985	187.571
CD4/CD8	0.000*	0.023	0.463	0.570	2.176	2.232	1.816	1.792

Columns 3-6 show the significance (P ) of effects of age, sex, latent toxoplasmosis and toxoplasmosis-sex interaction for the whole population, patients with seasonal allergic rhinitis and patients with immunodeficiencies. Columns 7-10 show the arithmetic means of various variables in particular subpopulations. The P value = 0.000 means P < 0.0005, the significant P -values (P < 0.05) are denoted with asterisks, the trends P < 0.10 are, printed in bold..

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