Skip to main content

Table 1 Summary of baseline characteristics and haematologic indices of study participants by HIV status

From: The influence of different helminth infection phenotypes on immune responses against HIV in co-infected adults in South Africa

Characteristics HIV-1 Positive (n = 151) HIV-1 Negative (n = 45)
Demographic characteristics   
Males 15 11
Females 136 34
Median Age (years) 30.6 40.0
Serum IgE and Helminth Infection Status   
Mean total IgE (Ref. range below 70 KU/L) 429.2 kU/L 655.18 kU/L
Mean Ascaris-specific IgE (Ref. range below 0.35 kU/L) 2.15 kU/L 2.86 kU/L
Helminth egg positive (number/total) % (51/124)a 41.1 (18/39)b 46.1
Helminth egg positive and/or positive serology* (99/151) 66.0 (32/45) 71. 1
Ascaris Worm Burden epg** Mean (SD) 170 (86.5) 191 (78.8)
Trichuris Worm Burden epg Mean (SD) 19.8 (36.7) 74.11 (56.2)
Haematological/Viral Indices (Median) (n = 149) (n = 45)
Total lymphocytes ( 1.0-4.0 × 109/L) 1.98 2.22
T lymphocytes (1.1-1.7 × 109/L ) 1.49 1.71
CD8+(0.5-0.9 × 109/L) 0.78 0.47
CD4+ (0.7-1.1 × 109/L) 0.32 0.74
CD4:CD8 ratio 1-1,5 0.4 1.58
NK cells (0.2-0.4 × 109/L) 0.1 0.18
B lymphocytes(0.2-0.4 × 109/L) 0.1 0.24
Median Viral load (copies/ml) 33 317 -
  1. *Evidence of helminth exposure as indicated by faecal egg excretion and/or elevated Ascaris lumbricoides specific IgE. ** Epg is eggs per gram of stool. a Twenty seven of 151 (HIV+) andb six of 45 ( HIV-) participants did not submit faecal samples. The haematological reference values in brackets were established for the local population at Tygerberg Hospital and their lower limits differ from those of the CDC reference ranges for CD4+ (0.475-1.616 × 109/L) and (CD8+:0.209- 0.924 × 109/L) [2729].