A large sustained endemic outbreak of multiresistant Pseudomonas aeruginosa: a new epidemiological scenario for nosocomial acquisition

Table 1 Antibiotic susceptibility of multiresistant P.aeruginosa clone strains

	Range	MIC₅₀	MIC₉₀	Breakpoint		%I^a	%R^b	Breakpoint		%I^a	R^b
				CLSI 2009				EUCAST2009
				S	R			S	R
PIP	≤ 16- > 64	64	> 64	≤ 64	≥128	-	39	≤ 16	> 16	-	97
TIC	≤ 16- > 64	64	> 64	≤ 64	≥128	-	42	≤ 16	> 16	-	98
TZP	≤ 16/4- > 64/4	64/4	> 64/4	≤ 64/4	≥128/4	-	35	≤ 16/4	> 16/4	-	93
ATM	2- > 16	16	> 16	≤ 8	≥32	85	14	≤ 1	> 16	85	14
CAZ	2- > 16	16	> 16	≤ 8	≥32	75	22	≤ 8	> 8	-	97
FEP	2- > 16	16	> 16	≤ 8	≥32	82	17	≤ 8	> 8	-	99
GEN	≤ 4- > 8	> 8	> 8	≤ 4	≥16	0	99	≤ 4	> 4	-	99
TOB	≤ 4- > 8	> 8	> 8	≤ 4	≥16	1	95	≤ 4	> 4	-	96
AMK	≤ 8- > 16	≤ 8	> 16	≤ 16	≥64	0	21	≤ 8	> 16	29	21
IPM	8- > 8	> 8	> 8	≤ 4	≥16	10	90	≤ 4	> 8	10	90
MEM	8- > 8	> 8	> 8	≤ 4	≥16	33	67	≤ 2	> 8	33	67
CIP	2- > 2	> 2	> 2	≤ 1	≥4	2	98	≤ 0.5	> 1		100
Colistin	≤ 2	≤ 2	≤ 2	≤ 2	≥4	0	0	≤ 2	> 2	0	0

^a Intermediate.
^b Resistant.
PIP = Piperacillin; TIC = Ticarcillin; TZP = Piperacillin-tazobactam; ATM = Aztreonam; CAZ = Ceftazidime; FEP = Cefepime; GEN = Gentamicin; TOB = Tobramycin; AMK = Amikacin; IPM = Imipenem; MEM = Meropenem; CIP = Ciprofloxacin.

ISSN: 1471-2334