Skip to main content

Advertisement

Table 2 Association of HIV and HIV/HCV infection with flow-mediated dilatation, carotid intima-media thickness, and circulating levels of cell adhesion molecules

From: Evaluation of endothelial function and subclinical atherosclerosis in association with hepatitis C virus in HIV-infected patients: a cross-sectional study

Variable Mean difference in log brachial artery FMD, % (95% CI) P Mean difference in log carotid IMT, mm
(95% CI)
P Mean difference in log sICAM-1, ηg/mL (95% CI) P Mean difference in log sVCAM-1, ηg/mL (95% CI) P
HIV/HCV vs. HIV         
Unadjusted 0.10 (-0.18-0.38) 0.47 -0.05 (-0.11-0.017) 0.15 0.36 (0.22-0.50) < 0.001 0.23 (-0.10-0.55) 0.01
Adjusted 0.17 (-0.33-0.68) 0.501 0.05 (-0.05-0.16) 0.273 0.39 (0.14-0.64) 0.0023 0.22 (0.05-0.39) 0.173
HIV/HCV vs. HIV
(patients with VL < 50 c/mL) 2
        
Unadjusted 0.009 (-0.33-0.34) 0.96 -0.08 (-0.16-0.003) 0.06 0.33 (0.14-0.52) 0.001 0.17 (-0.06-0.40) 0.14
Adjusted 0.23 (-0.45-0.90) 0.471 0.014 (-0.13-0.16) 0.243 0.55 (0.19-0.90) 0.0033 0.21 (-0.28-0.69) 0.253
  1. 1Adjusted for baseline brachial artery diameter, age, sex, C CDC category, intravenous drug use, men who have sex with men, current protease inhibitor use, lipid-lowering therapy, hypertension, diabetes, smoking, lipodystrophy, systolic blood pressure, fasting total cholesterol and LDL-cholesterol, APRI and FIB-4.
  2. 2N = 134
  3. 3Adjusted for sex, C CDC category, intravenous drug use, men who have sex with men, current protease inhibitor use, lipid-lowering therapy, smoking, systolic blood pressure, fasting total cholesterol and LDL-cholesterol, APRI and FIB-4.
  4. FMD, flow-mediated dilatation; IMT, intima-media thickness; HCV, hepatitis C virus; CI, confidence interval