Figure 3
From: Immunologically reactive M. leprae antigens with relevance to diagnosis and vaccine development
The ML0276 protein elicits a leprosy-specific cellular response but is detected by serum antibodies from all study groups. WBA-IFNγ and serum IgG responses against ML0276 are shown as an example of a protein specific for WBA IFNγ but that lacks specificity for serum IgG responses. WBA results are presented as box and whisker plots, with the boxes encompassing the 25th and 75th percentiles, and the black line within each box indicating the median value, n = 20 per group. Antibody results are shown in scatter plots of individual values for each individual serum tested, n = 45 per group. The dotted line indicates the calculated cut-off for positive responses (OD >0.3).