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Table 2 Comparison of malaria clinical signs and symptoms with blood smear results in patients admitted for severe malaria at Bombo hospital, Tanga, Tanzania

From: Prospective study on severe malaria among in-patients at Bombo regional hospital, Tanga, north-eastern Tanzania

 

Clinical observation alone

    

Signs & symptoms

Initial total cases*+

Reassessed cases (n,%)**+

No. +ve (n,%)

Odds ratio

P-value

95% CI

Clinical manifestations*

494

369 (74.7)

227 (61.5)

1.63

0.008

1.136 - 2.350

Cerebral malaria**

273

129 (47.3)

89 (69.0)

1.34

0.26

0.807 - 2.208

Severe anaemia

494

72 (14.6)

61 (84.7)

4.85

0.001

2.509 - 9.578

Hyperpyrexia†

494

97 (19.6)

59 (60.8)

1.17

0.486

0.746 - 1.849

Hyperparasitaemia††

494

285 (57.7)

4 (1.4)

 

0.085

 

Convulsions

494

23 (4.7)

17 (73.9)

2.15

0.107

0.831 - 5.540

Jaundice

494

6 (1.2)

3 (50.0)

0.73

0.701

0.146 - 3.656

  1. *+Initial total cases are those admitted with diagnosis of severe malaria from OPD
  2. **+Reassessed cases are those confirmed to have severe malaria by investigators.
  3. *Clinical signs and symptoms used as inclusion criteria for severe malaria
  4. **According to the Blantyre coma score scale
  5. †Axillary temperature ≥ 39.5°C
  6. ††Parasite count ≥ 250,000/μL of blood
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BMC Infectious Diseases

ISSN: 1471-2334

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