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Table 4 Concordance of PZase activity and PZA susceptibility testing by the BACTEC MGIT 960 method

From: Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan

  PZase activity Sensitivity (%) Specificity (%) PPV (%) NPV (%)
PZA susceptibility Negative      
Overall, n = 66    58.3 93.3 91.3 65.1
   Resistance 21 15     
   Susceptible 2 28     
Beijing strain, n = 37    66.7 93.8 93.3 68.2
   Resistance 14 7     
   Susceptible 1 15     
Non-Beijing strain, n = 29    46.7 92.9 87.5 61.9
   Resistance 7 8     
   Susceptible 1 13     
  1. PZase, pyrazinamidase; PZA, pyrazinamide; PPV, positive predictive value; NPV, negative predictive value.