Table 4 Concordance of PZase activity and PZA susceptibility testing by the BACTEC MGIT 960 method
From: Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan
| Â | PZase activity | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|---|
PZA susceptibility | Negative | Â | Â | Â | Â | Â |
Overall, n = 66 | Â | Â | 58.3 | 93.3 | 91.3 | 65.1 |
   Resistance | 21 | 15 |  |  |  |  |
   Susceptible | 2 | 28 |  |  |  |  |
Beijing strain, n = 37 | Â | Â | 66.7 | 93.8 | 93.3 | 68.2 |
   Resistance | 14 | 7 |  |  |  |  |
   Susceptible | 1 | 15 |  |  |  |  |
Non-Beijing strain, n = 29 | Â | Â | 46.7 | 92.9 | 87.5 | 61.9 |
   Resistance | 7 | 8 |  |  |  |  |
   Susceptible | 1 | 13 |  |  |  |  |