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Table 3 Concordance of pncA gene analysis and PZA susceptibility testing by the BACTEC MGIT 960 method

From: Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan

  pncA gene mutation Sensitivity (%) Specificity (%) PPV (%) NPV (%)
PZA susceptibility Yes      
Overall, n = 66    80.6 96.7 96.7 80.6
   Resistance 29 7     
   Susceptible 1 29     
Beijing strain, n = 37    76.2 93.8 94.1 75
   Resistance 16 5     
   Susceptible 1 15     
Non-Beijing strain, n = 29    86.7 100 100 87.5
   Resistance 13 2     
   Susceptible 0 14     
  1. PZA, pyrazinamide; PPV, positive predictive value; NPV, negative predictive value.