Table 3 Concordance of pncA gene analysis and PZA susceptibility testing by the BACTEC MGIT 960 method
From: Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan
| Â | pncA gene mutation | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|---|
PZA susceptibility | Yes | Â | Â | Â | Â | Â |
Overall, n = 66 | Â | Â | 80.6 | 96.7 | 96.7 | 80.6 |
   Resistance | 29 | 7 |  |  |  |  |
   Susceptible | 1 | 29 |  |  |  |  |
Beijing strain, n = 37 | Â | Â | 76.2 | 93.8 | 94.1 | 75 |
   Resistance | 16 | 5 |  |  |  |  |
   Susceptible | 1 | 15 |  |  |  |  |
Non-Beijing strain, n = 29 | Â | Â | 86.7 | 100 | 100 | 87.5 |
   Resistance | 13 | 2 |  |  |  |  |
   Susceptible | 0 | 14 |  |  |  |  |