Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial

Table 1 Spearman correlation between cord blood responses and maternal infection intensity at enrolment during pregnancy.

		Cytokine responses to SWA			Cytokine responses to SEA
		Spearman coefficients	p-value	p-value for difference between correlations	Spearman coefficients	p-value	p-value for difference between correlations
IFNγ	Placebo (n = 70)	0.0426	0.726	0.45	0.1326	0.274	0.26
	Praziquantel (n = 73)	-0.0901	0.449		-0.0634	0.594
IL-2	Placebo (n = 65)	0.2134	0.088	0.28	0.1468	0.243	0.21
	Praziquantel (n = 72)	0.0214	0.858		-0.0789	0.510
IL-4	Placebo (n = 66)	-0.1362	0.275	0.64	0.0064	0.960	0.98
	Praziquantel (n = 71)	-0.2166	0.070		0.0111	0.927
IL-5	Placebo (n = 70)	0.2744	0.021	0.09	0.2271	0.059	0.40
	Praziquantel (n = 74)	-0.0169	0.886		0.0830	0.482
IL-13	Placebo (n = 69)	0.2644	0.028	0.09	0.1554	0.202	0.39
	Praziquantel (n = 73)	-0.0331	0.781		0.0044	0.971
IL-10	Placebo (n = 69)	0.0178	0.885	0.77	-0.0384	0.754	0.92
	Praziquantel (n = 72)	0.0691	0.564		-0.0572	0.633

ISSN: 1471-2334