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Table 1 Clinical characteristics of ventilated and non ventilated patients

From: Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza

  MV (n = 15) NMV (n = 8)
Gender (M/F) 8/7 1/7
Age 47.00 (15.55) 37.50 (15.12)
Pandemic influenza vaccine (yes/no) 0/15 0/8
Chronic respiratory disease (yes/no) 3/12 2/6
Renal disease (yes/no) 1/14 2/6
Cardiovascular disease (yes/no) 2/13 0/8
Neurological disease (yes/no) 3/12 1/7
Cancer (yes/no) 0/15 1/7
Obesity (BMI > 30) (yes/no) 1/14 1/7
Diabetes (yes/no) 2/13 0/8
Pregnancy (yes/no) 1/14 2/6
Dyslipemia (yes/no) 2/13 0/8
Alcoholism (yes/no) 0/15 2/6
Smoker (yes/no) 9/6 4/4
Fatal outcome/survivors 7/8 0/8
Duration of symptoms at ICU admission 4.9 (3.6) 5.0 (2.2)
Pa O2/Fi O2 120.9 (55.5) 153.8 (69.7)
Days at hospital 20.9 (26.2) 4.5 (1.9)
Days since onset to intubation 5.1 (3.7) n.a
Oseltamivir 15/0 8/0
Duration of symptoms before oseltamivir 4.8 (3.7) 4.6 (2.4)
Bilateral infiltrates in chest X-Ray at admission to ICU (yes/no) 14/1 6/2
Bacterial overinfection during hospitalization (yes/no)
(resp culture-RC; hemoculture-HC)
4/11
S. marcescens RC, HC
S. aureus RC
P. aeruginosa RC
A. baumanii RC
0/8
Presence of specific antibodies against 2009 pandemic influenza at admission to ICU (titre > 1/40) (yes/no) 2/13 2/6
SOFA 6.4 (2.8) 4.0 (1.0)
Creatinine (ref value: 0.5 - 1.2 mg/dl) 0.8 (0.4) 1.9 (3.0)
AST (ref value: 2-38 U/l) 91.2 (65.3) 73.8 (39.9)
ALT (ref value: 2-41 U/l) 43.1 (31.0) 75.6 (59.9)
CPK (ref value: 24- 194 U/ml) 850.7 (827.0) 449.0 (697.8)
Leucocytes (4500-10000/mm 3) 6277.8 (3189.6) 7258.7 (3973.6)
Neutrophils (1900-8000/mm 3) 5431.0 (2888.6) 6268.6 (3771.4)
Lymphocytes (900-5200/mm 3) 691.5 (445.6) 636.5 (340.8)
  1. Gender: M: male, F: female. Obesity is considered as Body Mass Index, BMI > 30. PaO2 = pressure of oxygen in arterial blood; FiO2 = fraction of inspired oxygen. Bacterial culture notation: R.C: respiratory culture; HC: hemoculture. SOFA: Sequential Organ Failure Assessment score. AST: Aspartate transaminase. ALT: Alanine transaminase. CPK = creatine phosphokinase. Continuous variables are expressed as mean, (standard deviation)