Table 1 Characteristics of patients at baseline
Qualitative variable - N (%) | NNRTI group N = 671 | NRTI group N = 225 | P |
|---|---|---|---|
Gender [Male] | 536 (79.9%) | 182 (80.9%) | 0.7429 |
Risk factor for HIV acquisition | Â | Â | 0.6749 |
   IVDU | 148 (22.1%) | 46 (20.4%) |  |
   Homo-bisexual | 198 (29.5%) | 65 (28.4%) |  |
   Heterosexual | 254 (37.9%) | 83 (36.9%) |  |
   Other | 16 (2.4%) | 9 (4%) |  |
   Unknown | 55 (8.2%) | 22 (9.8%) |  |
Nationality | Â | Â | 0.6511 |
   Europe or North America | 608 (90.6%) | 208 (92.4%) |  |
   Other | 41 | 12 |  |
   Unknown | 22 | 5 |  |
HCV-Ab | Â | Â | 0.8498 |
   Positive | 169 (25.2%) | 55 (24.5%) |  |
   Negative | 432 (64.4%) | 149 (66.2%) |  |
   Unknown | 70 (10.4%) | 21 (9.3%) |  |
CDC '93 Class C | 200 (29.8%) | 64 (28.4%) | 0.6982 |
CD4+ classes | Â | Â | 0.0782 |
   ≥ 200/mm3 | 342 (51.0%) | 93 (41.3%) |  |
   201-350/mm3 | 146 (21.8%) | 56 (24.9%) |  |
   351-500/mm3 | 101 (15.0%) | 45 (20.0%) |  |
   > 500/mm3 | 82 (12.2%) | 31 (13.8%) |  |
Centre | Â | Â | 0.1448 |
   Master | 399 (59.5%) | 115 (51.1%) |  |
   Chelsea & Westminster | 97 (14.5%) | 38 (16.9%) |  |
   ICONA | 139 (20.7%) | 60 (26.7%) |  |
   HSR+Modena | 35 (5.3%) | 12 (5.3%) |  |
Calendar year at study initiation | Â | Â | 0.0137 |
   1997-2000 | 264 (39.3%) | 70 (31.1%) |  |
   2001-2003 | 309 (46.1%) | 129 (57.3%) |  |
   2004-2006 | 98 (14.6%) | 26 (11.6%) |  |
Boosted-PI as first line | 78 (11.6%) | 30 (13.3%) | 0.4957 |
Quantitative variables | Â | Â | Â |
Mean (SD) age [years] | 39 (35-45) | 38 (34-44) | 0.3680 |
Mean (SD) pre-treatment HIV-RNA [log10 copies/ml] | 5.012 (4.415-5.430) | 5.000 (4.511-5.519) | 0.6269 |
Median (IQR) CD4-count [cells/mm3] | 196 (86-377) | 249 (103-403) | 0.0234 |