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Table 3 The table summarizes the clinical and laboratory parameters studied in the NE patients categorized according to their major CNS complications and CSF PUUV IgM findings

From: Young male patients are at elevated risk of developing serious central nervous system complications during acute Puumala hantavirus infection

  No major CNS complications
(n = 21)
No major CNS complications
(n = 19)
Patients with major CNS complications
(n = 8)
CSF PUUV IgM negative positive  
Female (%) 47.6 15.8* 12.5*
Age (years) 52.9 45.7 38.5*
CSF white cells (x10e6/l) 1.5 4.7 6.5**
CSF protein (mg/l) 387 780** 1302***
B-thrombocytes (x10e9/l) 80 62 27**
B-white cells (x10e9/l) 7.4 11.3** 13.3**
B-Hb (g/l) 149 152 179**
P-CRP (mg/l) 100 63 149*
P-Creatinine (umol/l) 113 413*** 433***
BP, systolic (mmHg) 129 129 143
hospitalization (days) 5.0 5.1 9.3***
dialysis 0 0 0
  1. In each category, the percentage of female gender, mean age of the patients, mean CSF white cell count, and mean CSF protein concentration are given. Blood thrombocyte count (nadir), peak plasma creatinine level, blood white cell count and haemoglobin concentration at the time of hospital entry are reported. Systolic blood pressure (BP) at the time of hospital entry, length of hospitalization, and number of patients treated with dialysis are given. Statistical analysis is a comparion between the CSF PUUV IgM negative and positive cases, and the CSF PUUV IgM negative cases and the patients with major CNS complications. * indicates p < 0.05, ** p < 0.01, and *** p < 0.001.