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Table 2 Summary of the clinical properties of the 8 patients with major CNS involvement caused by acute NE

From: Young male patients are at elevated risk of developing serious central nervous system complications during acute Puumala hantavirus infection

Patient

gender

age

year

clinical symptoms

MRI finding

hormonal status

EEG

1

male

17

2009

confusion, seizures

cortical oedema

normal

excessive sleepiness

2

male

47

2006

confusion, somnolence

normal

normal

na

3

male

33

2006

transient vision loss,

vomiting

pituitary hemorrhage

panhypopuitarism,

recovered

normal

4

male

49

2007

confusion, somnolence, transient vision loss

pituitary hemorrhage

panhypopuitarism,

hormonal replacement

normal

5

female

47

2005

confusion, somnolence

pituitary hemorrhage

panhypopuitarism,

hormonal replacement

mildly increased delta activity

6

male

58

1999

transient vision loss,

sudden death

na

pituitary hemorrhage in autopsy

na

7

male

38

1991

confusion, somnolence

pituitary hemorrhage

panhypopuitarism,

hormonal replacement

mild disturbance

8

male

19

2000

confusion, seizures

pituitary hemorrhage

panhypopuitarism,

recovered

diffuse delta activity and temporal periodic postictal slowing

  1. Gender, age, year of their acute NE, brief description of their illness, brain MRI, hormonal status, and EEG is given.