Fraction of new infections when the HIV infectious (transmitter) individual has a co-infection (simulation 2). The model tracks the mechanism of the transmission of the infection. For the simulated period, if an HIV infection takes place, we recorded the presence in the infectious individual of any of the four infectious diseases included in the model, or in the case of HSV-2 due to the enhanced susceptibility caused by HSV-2 infection, we also recorded the presence of this infection on the susceptible individual and identified the cause of the amplification of the transmission caused by co-infection. (A) shows that HSV-2 was the most prevalent infection in co-infected individuals who transmitted the HIV infection, followed by malaria. This result is associated with the high prevalence of both infections in the general population. Grouping all STIs, more than 50% of the HIV infections were associated with an STI (B). More than 70% of the total HIV infections were caused by co-infected individuals (C).