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Table 5 Univariate analysis of prognostic factors for sequelae in childhood BM

From: Prognostic factors related to sequelae in childhood bacterial meningitis: Data from a Greek meningitis registry

  

All BM cases (n = 2382)

Confirmed cases (n = 1297)

Prognostic Factors

Sequelae/Prognostic factor*

(%)

RR

(95% CI)

P-value

Sequelae/Prognostic factor*

(%)

RR

(95% CI)

P-value

Etiology

   N. meningitidis

Yes

15/1091

(1.4)

0.26

(0.15-0.46)

< 0.001

15/763

(2.0)

0.22

(0.12-0.39)

< 0.001

 

No

58/1116

(5.2)

   

40/445

(9.0)

   

   S. pneumoniae

Yes

20/161

(12.4)

4.80

(2.94-7.82)

< 0.001

20/161

(12.4)

3.72

(2.20-6.27)

< 0.001

 

No

53/2046

(2.6)

   

35/1047

(3.3)

   

   H. influenzae

Yes

11/240

(4.6)

1.45

(0.78-2.72)

0.163

11/240

(4.6)

1.01

(0.53-1.92)

0.980

 

No

62/1967

(3.2)

   

44/968

(4.5)

   

   Other bacteria

Yes

9/44

(20.5)

6.91

(3.68-12.99)

< 0.001

9/44

(20.5)

5.18

(2.71-9.89)

< 0.001

 

No

64/2163

(3.0)

   

46/1164

(4.0)

   

   Unknown

Yes

18/671

(2.7)

0.75

(0.44-1.27)

0.170

-

-

-

-

-

 

No

55/1536

(3.6)

   

-

-

   

Various Characteristics

   Male sex

Yes

45/1296

(3.5)

1.12

(0.71-1.79)

0.356

33/690

(4.8)

1.12

(0.66-1.90)

0.669

 

No

28/907

(3.1)

   

22/516

(4.3)

   

   Duration of symptoms < 24 h

Yes

5/423

(1.2)

0.32

(0.13-0.80)

0.004

3/240

(1.3)

0.24

(0.07-0.75)

0.007

 

No

56/1524

(3.7)

   

44/828

(5.3)

   

   Age < 2 y

Yes

50/1038

(4.8)

2.43

(1.49-3.99)

< 0.001

39/624

(6.3)

2.15

(1.22-3.81)

0.007

 

No

22/1112

(2.0)

   

16/551

(2.9)

   

   Period C

Yes

11/384

(2.9)

0.84

(0.45-1.58)

0.364

11/247

(4.5)

0.97

(0.51-1.86)

0.933

 

No

62/1823

(3.4)

   

44/961

(4.6)

   
  1. * Prognostic factor population varies due to missing values
  2. Missing values ranged from 7.3% to 18.3%
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BMC Infectious Diseases

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