| N/Total (%) |  | |||||||
---|---|---|---|---|---|---|---|---|---|
Clinical Features | Age < 1 y (n = 786) | Age 1-4 y (n = 932) | Age 5-9 y (n = 480) | Age > = 10 y (n = 208) | P- value | ||||
All cases | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Fever | 383/408 | (93.9) | 421/459 | (91.7) | 225/236 | (95.3) | 101/109 | (92.7) | 0.303 |
   Shock | 66/541 | (12.2) | 84/646 | (13.0) | 35/317 | (11.0) | 18/140 | (12.9) | 0.849 |
   Coma | 29/525 | (5.5) | 58/639 | (9.1) | 33/317 | (10.4) | 32/145 | (22.1) | < 0.001 |
   Bulging Fontanellea | 371/637 | (58.2) | 37/235 | (15.7) | - | - | - | - | < 0.001 |
   Gruntinga | 372/646 | (57.6) | 91/260 | (35.0) | - | - | - | - | < 0.001 |
   Poor feeding | 330/603 | (54.7) | 103/585 | (17.6) | 0/257 | (0.0) | 4/121 | (3.3) | < 0.001 |
   Seizures | 155/600 | (25.8) | 134/678 | (19.8) | 24/316 | (7.6) | 14/137 | (10.2) | < 0.001 |
   Headacheb | - | - | 304/447 | (68.0) | 369/424 | (87.0) | 167/189 | (88.4) | < 0.001 |
   Meningeal signsc | - | - | 655/811 | (80.8) | 360/426 | (84.5) | 151/182 | (83.0) | 0.252 |
   Haemorrhagic rash | 225/786 | (28.6) | 452/930 | (48.6) | 190/479 | (39.7) | 76/207 | (36.7) | < 0.001 |
   Vomiting | 269/622 | (43.2) | 477/792 | (60.2) | 289/424 | (68.2) | 123/179 | (68.7) | < 0.001 |
Confirmed cases | Â | Â | Â | Â | Â | Â | Â | Â | |
   Fever | 218/231 | (94.4) | 270/286 | (94.4) | 102/108 | (94.4) | 44/46 | (95.7) | 0.988 |
   Shock | 40/312 | (12.8) | 48/397 | (12.1) | 20/144 | (13.9) | 6/56 | (10.7) | 0.918 |
   Coma | 18/301 | (6.0) | 37/394 | (9.4) | 24/148 | (16.2) | 14/57 | (24.6) | < 0.001 |
   Bulging Fontanellea | 242/359 | (67.4) | 23/159 | (14.5) | - | - | - | - | < 0.001 |
   Gruntinga | 243/369 | (65.9) | 66/185 | (35.7) | - | - | - | - | < 0.001 |
   Poor feeding | 205/339 | (60.5) | 77/361 | (21.3) | 0/117 | (0.0) | 3/46 | (6.5) | < 0.001 |
   Seizures | 93/343 | (27.4) | 86/418 | (20.6) | 11/142 | (7.7) | 7/54 | (13.0) | < 0.001 |
   Headacheb | - | - | 174/250 | (69.6) | 157/183 | (85.8) | 66/75 | (88.0) | < 0.001 |
   Meningeal signsc | - | - | 414/501 | (82.6) | 148/183 | (80.9) | 55/70 | (78.6) | 0.660 |
   Haemorrhagic rash | 119/440 | (27.0) | 274/570 | (48.1) | 102/204 | (50.0) | 39/80 | (48.8) | < 0.001 |
   Vomiting | 167/357 | (46.8) | 310/490 | (63.3) | 128/184 | (69.6) | 53/72 | (73.6) | < 0.001 |