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Table 4 Multivariate analysis for factors related to high-ferritin concentrations among ART-naïve patients (n = 95) in Hasan Sadikin Hospital, September 2007 - August 2009

From: Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia

   

Base analysis

Sensitivity analysis

 

n

high ferritin

Univariate

Multivariate

Multivariate

   

OR

(95% CI)

p value

OR adjusted

(95% CI)

p value

OR adjusted (95% CI)

p value

Gender

        

   Female

27

12

1

 

1

 

1

 

   Male

68

52

4.1 (1.6-10.4)

0.004

1.5 (0.5-5.1)

0.47

1.8 (0.50-6.2)

0.39

Anemia

        

   No anemia

15

10

1

     

   Mild

56

35

0.8 (0.3-2.8)

0.77

    

   Moderate - severe

24

19

1.9 (0.4-8.2)

0.39

    

hsCRP (mg/L)

        

   < 5

41

21

1

 

1

 

1

 

   > 5

54

43

3.7 (1.5-9.2)

0.004

3.8 (1.3-10.9)

0.01

2.8 (0.9-8.4)

0.07

CD4 (cells/mL)

        

   > 50

33

12

1

 

1

 

1

 

   0-50

60

51

9.9 (3.6-27.0)

< 0.001

10.0 (3.5-28.8)

< 0.001

6.8 (2.2-20.3)

0.001

Anti HCV

        

   Negative

19

9

1

     

   Positive

36

25

2.5 (0.8-7.9)

0.11

    
  1. *CD4 cell counts were missing in 2 patients, HCV serostatus in 40 patients.
  2. Sensitivity analysis: subjects with TB treatment within 3 months presentation excluded from analysis
  3. High ferritin: > 400 ng/mL for men or > 150 ng/mL for women
  4. Mild anemia: Hb 10.5 - 12.99 g/dL for men; and 10.5 - 11.99 g/dL for women, moderate-severe anemia: Hb < 10.5 g/dL.
  5. ART, anti retroviral; OR, odd ratio; hsCRP, high sensitive C-reactive protein; HCV, hepatitis virus C.