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Table 4 Multivariate analysis for factors related to high-ferritin concentrations among ART-naïve patients (n = 95) in Hasan Sadikin Hospital, September 2007 - August 2009

From: Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia

    Base analysis Sensitivity analysis
  n high ferritin Univariate Multivariate Multivariate
    OR
(95% CI)
p value OR adjusted
(95% CI)
p value OR adjusted (95% CI) p value
Gender         
   Female 27 12 1   1   1  
   Male 68 52 4.1 (1.6-10.4) 0.004 1.5 (0.5-5.1) 0.47 1.8 (0.50-6.2) 0.39
Anemia         
   No anemia 15 10 1      
   Mild 56 35 0.8 (0.3-2.8) 0.77     
   Moderate - severe 24 19 1.9 (0.4-8.2) 0.39     
hsCRP (mg/L)         
   < 5 41 21 1   1   1  
   > 5 54 43 3.7 (1.5-9.2) 0.004 3.8 (1.3-10.9) 0.01 2.8 (0.9-8.4) 0.07
CD4 (cells/mL)         
   > 50 33 12 1   1   1  
   0-50 60 51 9.9 (3.6-27.0) < 0.001 10.0 (3.5-28.8) < 0.001 6.8 (2.2-20.3) 0.001
Anti HCV         
   Negative 19 9 1      
   Positive 36 25 2.5 (0.8-7.9) 0.11     
  1. *CD4 cell counts were missing in 2 patients, HCV serostatus in 40 patients.
  2. Sensitivity analysis: subjects with TB treatment within 3 months presentation excluded from analysis
  3. High ferritin: > 400 ng/mL for men or > 150 ng/mL for women
  4. Mild anemia: Hb 10.5 - 12.99 g/dL for men; and 10.5 - 11.99 g/dL for women, moderate-severe anemia: Hb < 10.5 g/dL.
  5. ART, anti retroviral; OR, odd ratio; hsCRP, high sensitive C-reactive protein; HCV, hepatitis virus C.