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Table 2 Multivariate analysis for factors related to six-month mortality among ART-naïve patients (n = 611) in Hasan Sadikin Hospital, September 2007 - August 2009

From: Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia

    Base Analysis Sensitivity Analysis
  n Mortality Univariate Multivariate Multivariate
    HR (95% CI) p value HR adjusted (95% CI) p value HR adjusted (95% CI) p value
Gender         
   Female 194 5 1   1   1  
   Male 416 29 2.8 (1.1-7.4) 0.03 1.5 (0.5-4.3) 0.46 1.8 (0.5-6.2) 0.32
Age (years old)         
   < 29 317 11 1   1   1  
   ≥29 294 23 2.3 (1.1-4.9) 0.02 1.6 (0.7-3.5) 0.24 1.4 (0.5-6.2) 0.49
CD4 (cells/mL)         
   > 50 353 4 1   1   1  
   ≤ 50 248 29 11.6 (4.0-33.3) < 0.001 5.7 (1.8-17.8) 0.003 6. 1 (1.6-23.1) 0.008
BMI (kg/m2)         
   ≥18.5 183 9 1      
   < 18.5 299 13 1.1 (0.5-2.7) 0.77     
Anemia, (%)         
   No anemia 304 4 1   1   1  
   Mild 186 10 3.8 (1.2-12.6) 0.03 2.2 (0.6-7.6) 0.21 2.6 (0.6-11.1) 0.19
   Moderate and severe 114 20 16.0 (5.3-47.9) < 0.001 6.5 (2.0-21.2) 0.002 10.9 (2.7-44.3) 0.001
History of IDU, (%)         
   No 209 11 1      
   Yes 357 21 1.1 (0.5-2.4) 0.76     
ART, (%)         
   No 324 14 1      
   Yes 287 20 1.7 (0.8-3.3) 0.12     
  1. *Data were missing for gender (n = 1), CD4 (n = 10), BMI in 482 patients (n = 129), anemia status (n = 7), history of IDU (n = 45).
  2. Sensitivity analysis: subjects with TB treatment within 3 months presentation excluded from analysis
  3. Mild anemia: Hb 10.5 - 12.99 g/dL for men; and 10.5 - 11.99 g/dL for women, moderate-severe anemia: Hb < 10.5 g/dL.
  4. ART: receive ART within 6 of presentation.
  5. BMI, body mass index; IDU: injecting drug user; ART, anti retroviral; HR, hazard ratio;