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Table 2 Multivariate analysis for factors related to six-month mortality among ART-naïve patients (n = 611) in Hasan Sadikin Hospital, September 2007 - August 2009

From: Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia

   

Base Analysis

Sensitivity Analysis

 

n

Mortality

Univariate

Multivariate

Multivariate

   

HR (95% CI)

p value

HR adjusted (95% CI)

p value

HR adjusted (95% CI)

p value

Gender

        

   Female

194

5

1

 

1

 

1

 

   Male

416

29

2.8 (1.1-7.4)

0.03

1.5 (0.5-4.3)

0.46

1.8 (0.5-6.2)

0.32

Age (years old)

        

   < 29

317

11

1

 

1

 

1

 

   ≥29

294

23

2.3 (1.1-4.9)

0.02

1.6 (0.7-3.5)

0.24

1.4 (0.5-6.2)

0.49

CD4 (cells/mL)

        

   > 50

353

4

1

 

1

 

1

 

   ≤ 50

248

29

11.6 (4.0-33.3)

< 0.001

5.7 (1.8-17.8)

0.003

6. 1 (1.6-23.1)

0.008

BMI (kg/m2)

        

   ≥18.5

183

9

1

     

   < 18.5

299

13

1.1 (0.5-2.7)

0.77

    

Anemia, (%)

        

   No anemia

304

4

1

 

1

 

1

 

   Mild

186

10

3.8 (1.2-12.6)

0.03

2.2 (0.6-7.6)

0.21

2.6 (0.6-11.1)

0.19

   Moderate and severe

114

20

16.0 (5.3-47.9)

< 0.001

6.5 (2.0-21.2)

0.002

10.9 (2.7-44.3)

0.001

History of IDU, (%)

        

   No

209

11

1

     

   Yes

357

21

1.1 (0.5-2.4)

0.76

    

ART, (%)

        

   No

324

14

1

     

   Yes

287

20

1.7 (0.8-3.3)

0.12

    
  1. *Data were missing for gender (n = 1), CD4 (n = 10), BMI in 482 patients (n = 129), anemia status (n = 7), history of IDU (n = 45).
  2. Sensitivity analysis: subjects with TB treatment within 3 months presentation excluded from analysis
  3. Mild anemia: Hb 10.5 - 12.99 g/dL for men; and 10.5 - 11.99 g/dL for women, moderate-severe anemia: Hb < 10.5 g/dL.
  4. ART: receive ART within 6 of presentation.
  5. BMI, body mass index; IDU: injecting drug user; ART, anti retroviral; HR, hazard ratio;
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BMC Infectious Diseases

ISSN: 1471-2334

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