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Table 4 Characteristics associated with mortality during follow-up in untreated HIV-infected children.

From: Severe morbidity and mortality in untreated HIV-infected children in a paediatric care programme in Abidjan, Côte d'Ivoire, 2004-2009

      Univariate analysis Ajusted analysis
         Full model Reduced model
Variable # patients # events Observed rate (/100 CY) sHR† 95%CI‡ P sHR 95%CI P sHR 95%CI P
Overall   405 21 3.26          
Age at baseline (years)       0.034    0.840    0.097
  < 1 64 9 9.70 1 -   1 -   1 -  
  [1 - 2] 42 2 3.40 0.32 (0.07 - 1.48)   0.76 (0.08 - 6.38)   0.6 (0.11 - 3.23)  
  [2 - 5] 108 3 1.68 0.2 (0.05 - 0.74)   0.44 (0.07 - 2.70)   0.34 (0.08 - 1.39)  
  [5 - 10] 142 5 1.82 0.24 (0.08 - 0.71)   0.39 (0.06 - 2.31)   0.29 (0.10 - 0.80)  
  [10 - 15] 49 2 4.91 0.28 (0.06 - 1.29)   0.44 (0.05 - 4.26)   0.28 (0.06 - 1.19)  
Immunodeficiency       0.001    0.003    0.0025
  No 112 6 1.36 1 -   1 -   1 -  
  Yes 106 2 3.38 5.21 (1.00 - 25.60)   6.8 (1.51 - 30.57)   6.02 (1.28 - 28.42)  
  Unknown 98 13 8.90 13.82 (3.16 - 60.50)   12.93 (2.95 - 56.68)   12.6 (2.94 - 53.97)  
Gender        0.920    0.770    0.670
  Male 216 11 3.09 1 -   1 -   1 -  
  Female 189 10 3.45 1.05 (0.47 - 2.45)   1.15 (0.44 - 2.98)   1.22 (0.49 - 3.04)  
History of a PMTCT intervention      0.019    0.590    
  No 267 11 2.80 1 -   1 -     
  Yes 65 8 6.73 2.96 (1.19 - 7.33)   0.92 (0.14 - 6.21)     
  Unknown 73 2 1.48 0.63 (0.14 - 2.83)   0.47 (0.11 - 2.05)     
Mother known to be deceased      0.140    0.230    
  No 308 19 3.59 1 -   1 -     
  Yes 97 2 1.72 3.01 (0.71 - 12.80)   2.78 (0.53 - 14.68)     
Cotrimoxazole prophylaxis at baseline     0.150    0.830    
  No 134 11 4.93 1 -   1 -     
  Yes 271 10 2.36 0.53 (0.23 - 1.25)   1.13 (0.37 - 3.43)     
Follow-up Centre       0.550       
  Cepref 131 15 3.34 1 -        
  MTCT 92 6 3.05 1.33 (0.52 - 3.45)        
  1. Children followed-up over 18 months by the CePReF and the MTCT-Plus programme, Abidjan, Côte d'Ivoire (January-2004-December 2009). n = 405. Fine and Gray Model. CY: Child Years; †sHR: subdistribution hazard ratio; ‡95% confidence interval