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Table 3 Risk of bias assessment of eligible studies included in a meta-analysis of prolonged infusion versus intermittent infusion of β-lactams in hospitalized patients

From: Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials

Study Funding Source Allocation Sequence Adequately Generated Allocation Concealment Masking Similar Rates of Withdrawals Between Groups Intention to Treat Analysis
Angus 2000 Wellcome Trust of Great Britain Unclear Unclear Unclear Yes No
Bodey 1979 Pharmaceutical company Yes Yes Unclear Unclear Yes
Buck 2005 Pharmaceutical company Unclear Unclear No Yes Yes
Georges 2005 Not specified Unclear Unclear No Yes Yes
Hanes 2000 Pharmaceutical company Unclear Unclear Unclear Yes No
Kojika 2005 Not specified Unclear No No Yes Yes
Lagast 1983 Pharmaceutical company Unclear Unclear Unclear Yes Yes
Lau 2006 Pharmaceutical company Unclear Unclear No Yes No
Lubasch 2003 Pharmaceutical company Unclear Unclear No Unclear Unclear
Merchant 2008 Pharmaceutical company Unclear Unclear No Yes Yes
Nicolau 2001 Pharmaceutical company Yes Unclear No Yes No
Rafati 2006 Tehran University Medical Sciences Research Board Unclear Unclear No Yes Yes
Roberts 2007 National Health & Medical Research Council Yes Yes Yesa Yes Yes
Van Zanten 2006 Pharmaceutical company Unclear Unclear No No No
  1. aOnly outcome assessors were masked