Table 3 Risk of bias assessment of eligible studies included in a meta-analysis of prolonged infusion versus intermittent infusion of β-lactams in hospitalized patients
Study | Funding Source | Allocation Sequence Adequately Generated | Allocation Concealment | Masking | Similar Rates of Withdrawals Between Groups | Intention to Treat Analysis |
|---|---|---|---|---|---|---|
Angus 2000 | Wellcome Trust of Great Britain | Unclear | Unclear | Unclear | Yes | No |
Bodey 1979 | Pharmaceutical company | Yes | Yes | Unclear | Unclear | Yes |
Buck 2005 | Pharmaceutical company | Unclear | Unclear | No | Yes | Yes |
Georges 2005 | Not specified | Unclear | Unclear | No | Yes | Yes |
Hanes 2000 | Pharmaceutical company | Unclear | Unclear | Unclear | Yes | No |
Kojika 2005 | Not specified | Unclear | No | No | Yes | Yes |
Lagast 1983 | Pharmaceutical company | Unclear | Unclear | Unclear | Yes | Yes |
Lau 2006 | Pharmaceutical company | Unclear | Unclear | No | Yes | No |
Lubasch 2003 | Pharmaceutical company | Unclear | Unclear | No | Unclear | Unclear |
Merchant 2008 | Pharmaceutical company | Unclear | Unclear | No | Yes | Yes |
Nicolau 2001 | Pharmaceutical company | Yes | Unclear | No | Yes | No |
Rafati 2006 | Tehran University Medical Sciences Research Board | Unclear | Unclear | No | Yes | Yes |
Roberts 2007 | National Health & Medical Research Council | Yes | Yes | Yesa | Yes | Yes |
Van Zanten 2006 | Pharmaceutical company | Unclear | Unclear | No | No | No |