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Table 1 Baseline characteristics of 432 patients chronically infected with HCV, treated with peginterferon and ribavirin in Denmark between 1 January 2002 and 1 January 2007

From: Effectiveness of treatment with pegylated interferon and ribavirin in an unselected population of patients with chronic hepatitis C: A Danish nationwide cohort study

  

Whole cohort

  

SVR

Non-SVR

Total

 

274

158

Gender

Male

177 (64.5)

105 (66.5)

Nationality

European

226 (82.5)

146 (92.4)

 

Non-European

48 (17.5)

12 (7.6)

Route of infection

IDU

145 (52.9)

74 (46.8)

 

non-IDU

37 (13.5)

30 (19.0)

 

Unknown

92 (33.6)

54 (34.2)

Age at treatment initiation

≤ 45 years

148 (54.0)

49 (31.0)

Genotype

1

59 (21.5)

74 (46.8)

 

2

37 (13.5)

13 (8.2)

 

3

168 (61.3)

67 (42.4)

 

4

6 (2.2)

4 (2.5)

 

6

2 (0.7)

0

 

Unknown

2 (0.7)

0

HCV-RNA

> 600.000 IU/mL

92 (33.6)

77 (48.7)

Elevated ALT

2 × UNL*

149 (54.4)

73 (46.2)

Treating

Department (speciality)

Infectious Diseases

177 (64.6)

101 (63.9)

 

Gastroenterology/Hepatology

97 (35.4)

57 (36.1)

Liver biopsy within 3 years

Yes

152 (55.5)

98 (62.0)

Treatment completion

As planned

193 (70.4)

65 (41.1)

 

With dose reduction

55 (20.1)

43 (27.2)

 

Ended before scheduled

24 (8.8)

39 (24.7)

 

Unknown

2 (0.7)

11 (7.0)

  1. Data according to those achieving sustained virological response (SVR) versus non-SVR.
  2. Numbers in parenthesis is % of persons with SVR and non-SVR respectively.
  3. UNL, upper normal limit
  4. *2 × UNL = ALT > 70 IU/L (female), ALT > 100 IU/L (male)
  5. IDU, Intravenous drug use