Outbreak of Pneumonia in the Setting of Fatal Pneumococcal Meningitis among US Army Trainees: Potential Role of Chlamydia pneumoniae Infection

Table 2 Factors associated with pneumococcal carriage or C. pneumoniae detection among Alpha and Hotel Company trainees

	S. pneumoniae positive	S. pneumoniae negative	OR (CI)
	n = 49	n = 275
Receipt of antibiotics^a	7/37 (19%)	82/240 (34%)	0.4 (0.2-1.1)
"Bay" resident (> 4 trainees per room)	35 (71%)	191 (69%)	1.1 (0.6-2.2)
Current smoker	30 (61%)	142 (52%)	1.5 (0.8-2.8)
Floor of barracks
Floor 1	7/42 (17%)	64/233 (28%)	0.6 (0.2-1.6)
Floor 2	20/42 (47%)	87/233 (37%)	1.3 (0.6-2.6)
Floor 3	15/42 (36%)	82/233 (35%)	1 (Ref)^b
One or more symptoms^c	35 (71%)	229 (83%)	0.5 (0.3-1.0)
	*C. pneumoniae* positive	*C. pneumoniae* negative ^d	OR (CI)
	n = 37	n = 48
Receipt of antibiotics^a	25 (69%)	34 (71%)	0.9 (0.3-2.3)
"Bay" resident (> 4 trainees per room)	30 (81%)	31 (65%)	2.4 (0.9-6.5)
Current smoker	18 (49%)	16 (33%)	1.9 (0.8-4.6)
Floor of barracks
Floor 1	2/34 (6%)	9/45 (20%)	0.2 (0-1.0)
Floor 2	11/34 (32%)	15/45 (33%)	0.6 (0.2-1.7)
Floor 3	21/34 (62%)	18/45 (40%)	1 (Ref)^b

^aTrainee reported taking antibiotics during February 1-19, 2009
^bTrainees living on the 3rd floor of the barracks were used as the reference group for comparison with trainees living on the first and second floors of the barracks
^cOf the following symptoms: fever, chills, cough with or without sputum, difficulty breathing, wheezing, runny nose, sore throat or ear pain
^d Two Alpha Company trainees with respiratory specimens that were negative for C. pneumoniae were not included in univariate analysis including one trainee who had a sample that could not be linked back to the survey data and one trainee who gave a respiratory specimen but did not complete a survey

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