Skip to main content

Table 1 Summary of 26 patients with rheumatoid arthritis who developed histoplasmosis infection

From: Histoplasmosis infection in patients with rheumatoid arthritis, 1998-2009

Characteristic

Number (%) or years

Male

15 (58%)

Age, years (mean; range)

60 (32 - 78)

Duration of rheumatoid arthritis, years (mean; range)

10.5 (0.5 - 24)

Current disease modifying antirheumatic drug therapy

25 (96%)

Hospitalized for infection

15 (58%)

Duration of follow up, years (mean; range)

2.1 (0 - 7.9)

Patient deaths

2 (5%)

Medication

Number (%)

Methotrexate

21 (81%)

Prednisone (average dose: 9.1 mg)

15 (58%)

Hydroxychloroquine

5 (19%)

Leflunomide

5 (19%)

Anti-TNF Agent

15 (58%)

   Adalimumab

7 (27%)

   Infliximab

6 (23%)

   Etanercept

2 (8%)

Basis for Histoplasmosis Diagnosis

Number positive (%)

Fever

19 (73%)

Abnormal chest imaging (X-ray or CT)

22 (85%)

Histoplasma serology

23 (88%)

Histoplasma culture

14 (54%)

Histoplasma urinary antigen

13 (50%)

Histoplasma biopsy histopathology

12 (46%)