From: Histoplasmosis infection in patients with rheumatoid arthritis, 1998-2009
Characteristic | Number (%) or years |
---|---|
Male | 15 (58%) |
Age, years (mean; range) | 60 (32 - 78) |
Duration of rheumatoid arthritis, years (mean; range) | 10.5 (0.5 - 24) |
Current disease modifying antirheumatic drug therapy | 25 (96%) |
Hospitalized for infection | 15 (58%) |
Duration of follow up, years (mean; range) | 2.1 (0 - 7.9) |
Patient deaths | 2 (5%) |
Medication | Number (%) |
Methotrexate | 21 (81%) |
Prednisone (average dose: 9.1 mg) | 15 (58%) |
Hydroxychloroquine | 5 (19%) |
Leflunomide | 5 (19%) |
Anti-TNF Agent | 15 (58%) |
   Adalimumab | 7 (27%) |
   Infliximab | 6 (23%) |
   Etanercept | 2 (8%) |
Basis for Histoplasmosis Diagnosis | Number positive (%) |
Fever | 19 (73%) |
Abnormal chest imaging (X-ray or CT) | 22 (85%) |
Histoplasma serology | 23 (88%) |
Histoplasma culture | 14 (54%) |
Histoplasma urinary antigen | 13 (50%) |
Histoplasma biopsy histopathology | 12 (46%) |