Skip to main content

Table 2 Antibiogram of implicated pathogens in the super-infections of the study patients with adult bacterial meningitis (n = 21)

From: Clinical characteristics and therapeutic outcomes of nosocomial super-infection in adult bacterial meningitis

Case

Pathogens

ROC

CAZ

MAX

MEP

CIP

TIG

TMP-SMX

AMP- SBM

1

ESBL-Escherichia coli

R

R

R

S

 

S

  

2

Stenotrophomonas maltophilia

    

S

 

R

 
      

R

 

R

 

3

Acinetobacter baumannii

 

I

S

S

R

  

S

   

S

S

R

R

  

S

4

Enterobacter cloacae

 

S

 

S

S

   
 

Pseudomonas aeruginosa

 

S

S

S

S

   

5

Enterobacter cloacae

S

S

 

S

S

   

6

Acinetobacter baumannii

 

S

S

S

S

   
   

I

S

S

S

   

7

Acinetobacter spp

I

S

S

S

S

  

S

8

Acinetobacter spp

S

S

S

S

S

  

S

9

Pseudomonas aeruginosa

 

S

S

S

S

   
   

R

S

S

    

10

Acinetobacter baumannii

 

S

S

S

S

   

11A

Serratia marcescens

I

R

R

S

    
 

Stenotrophomonas maltophilia

    

S

 

S

 

11C

Stenotrophomonas maltophilia

    

R

 

S

 

12

Pseudomonas aeruginosa

 

S

S

S

S

   
   

R

S

S

R

   
 

ESBL-Proteus mirabilis

R

R

S

S

R

   

13

Pseudomonas putida

 

S

S

R

S

   
 

Acinetobacter spp

R

R

R

I

R

S

 

I

14

Serratia marcescens

S

S

S

S

S

   
 

Acinetobacter baumannii

 

R

R

R

R

S

 

R

15A

Morganella morganii

R

S

S

S

S

   
 

Proteus mirabilis

R

R

R

S

R

   

15B

Glucose non-fermenting bacilli

R

R

R

R

I

   

16

Stenotrophomonas maltophilia

    

S

 

S

 
 

Pseudomonas aeruginosa

 

R

R

S

S

   

17

Acinetobacter lwoffii

 

S

 

S

S

   
 

Pseudomonas aeruginosa

 

S

 

S

S

   

18A

Escherichia coli

 

R

S

S

    

18B

Acinetobacter baumannii

 

R

I

S

R

  

R

18D

Stenotrophomonas maltophilia

    

S

   

19

Escherichia coli

S

S

S

S

    
 

Enterobacter cloacae

S

S

S

S

   

R

21

Enterobacter aerogenes

I

I

S

S

S

   
  

R

R

S

S

S

   
  1. Abbreviations: ROC, ceftriaxone; CAZ, ceftazidime; MAX, cefepime; MEP, meropenem; CIP, ciprofloxacin; AMP-SBM, ampicillin-subactam; TIG, tigecycline; TMP-SMX, trimethoprime-sulfamethoxazole; LEV, levofloxacin; ESBL, extended spectrum β-lactamase; R, resistant; I, intermediate; S, susceptible
  2. Note: ESBL-producing Escherichia coli was suspected by the disk-diffusion susceptibility test [10].
  3. Non-Cephalosporin-susceptible Gram-negative bacteria (GNB) were used to describe isolates that were non-susceptible to ceftriaxone, ceftazidime, and cefepime. Intermediate and resistant isolates were considered non-susceptible [11]. Multi-drugs resistant (MDR) GNB was used to describe isolates that were non-susceptible to all antibiotics routinely tested including amikacin, (ampicillin-sulbactam in A. baumannii), ceftriaxone, ceftazidime, cefepime, ciprofloxacin, imepenem, and meropenem [12, 13]. The antimicrobial susceptibilities TMP-SMX, ciprofloxacin, levofloxacin, and moxifloaxcin of the Stenotrophomonas maltophilia strains isolated from the cerebrospinal fluid were determined concomitantly by the broth dilution method as described in the Clinical and Laboratory Standards (CLSI) guidelines.
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us