|
Drug
|
Method
|
MIC values
|
% of R strains
|
CA%
|
% of isolates with discrepant results
|
|---|
| | |
Ranges
|
50%
|
90%
| | |
Minor
|
Major
|
Very major
|
|---|
| |
CLSI
|
0.12-2
|
0.5
|
1
|
2.6
| | | | |
|
Amphotericin B
|
Etest
|
0.032-8
|
0.19
|
0.38
|
0.2
|
97.5
|
-
|
-
|
2.5
|
| |
Sensititre
|
0.03-2
|
0.5
|
1
|
0.4
|
97.3
|
-
|
0.2
|
2.5
|
| |
CLSI
|
<0.008-≥16
|
0.12
|
16
|
3.6
| | | | |
|
Anidulafungin
|
Etest
|
≤0.002-≥32
|
0.008
|
1.5
|
3.8
|
94.7
|
-
|
2.1
|
3.2
|
| |
Sensititre
|
≤0.008-≥16
|
0.06
|
1
|
1.7
|
96.4
|
-
|
-
|
3.6
|
| |
CLSI
|
0.016-≥16
|
1
|
2
|
6.7
| | | | |
|
Caspofungin
|
Etest
|
0.012-≥32
|
0.19
|
0.75
|
2.2
|
95.0
|
-
|
0.2
|
4.8
|
| |
Sensititre
|
0.015-≥16
|
0.12
|
0.5
|
2.2
|
95.3
|
-
|
-
|
4.7
|
| |
CLSI
|
≤0.12-128
|
0.5
|
16
|
3.3
| | | | |
|
Fluconazole
|
Etest
|
0.032-≥256
|
0.38
|
8
|
2.2
|
91.1
|
7.7
|
0.2
|
1
|
| |
Sensititre
|
≤0.12-≥256
|
0.5
|
16
|
2.7
|
89.8
|
0.2
|
0.2
|
9.8
|
|
Itraconazole
|
CLSI
|
0.008-≥16
|
0.25
|
1
|
7.8
| | | | |
| |
Etest
|
0.004-≥32
|
0.064
|
1.5
|
8.9
|
47.7
|
49.2
|
-
|
3.1
|
| |
Sensititre
|
≤0.008-≥8
|
0.03
|
1
|
5.9
|
46.8
|
59.2
|
-
|
4.0
|
|
Posaconazole
|
CLSI
|
≤0.008-≥8
|
0.12
|
1
|
6.5
| | | | |
| |
Etest
|
0.003-≥32
|
0.064
|
0.5
|
10.6
|
93.4
|
4.8
|
1.6
|
0.2
|
| |
Sensititre
|
≤0.008-≥8
|
0.03
|
1
|
2.3
|
96.0
|
3.5
|
-
|
0.5
|
|
Voriconazole
|
CLSI
|
≤0.008-8
|
0.016
|
0.25
|
1.9
| | | | |
| |
Etest
|
≤0.002-≥32
|
0.023
|
0.25
|
1.4
|
98.8
|
0.9
|
-
|
0.3
|
| |
Sensititre
|
≤0.008-8
|
0.008
|
0.25
|
1.1
|
98.3
|
1.0
|
0.2
|
0.5
|
- * Categorical Agreement (MIC values that fell within the same interpretive categories)
