Skip to main content

Table 1 Relevant clinical and laboratory data at hospital presentation and within seven days of dengue diagnosis

From: Confirmed adult dengue deaths in Singapore: 5-year multi-center retrospective study

 

No.(%) of patients

at presentation

No.(%) of patients

within seven days

of positive dengue

p*

WHO 1997 criteria for probable dengue

   

   Fever/temperature ≥37.5°C plus two or more of the following:

4 (14.3)

9 (32.1)

0.205

Fever:

   

Fever symptom

21 (75.0)

25 (89.3)

0.296

Temperature ≥37.5°C

19 (67.9)

25 (89.3)

0.101

Symptom/temperature ≥37.5°C

24 (85.7)

27 (96.4)

0.352

Headache

3 (10.7)

4 (14.3)

1.000

Retro-orbital pain

0 (0.0)

0 (0.0)

na

Myalgia

7 (25.0)

9 (32.1)

0.768

Arthralgia

0 (0.0)

2 (7.1)

0.491

Rash

1 (3.6)

3 (10.7)

0.611

Hemorrhagic manifestation

5 (17.9)

6 (21.4)

1.000

Leukopenia

6 (21.4)

11 (39.3)

0.245

WHO 2009 criteria for probable dengue

   

   Fever symptom/temperature ≥37.5°C and two of the following:

17 (60.7)

22 (78.6)

0.245

Fever symptom/temperature ≥37.5°C

24 (85.7)

27 (96.4)

0.352

Nausea or vomiting

10 (35.7)

10 (35.7)

na

Rash

1 (3.6)

3 (10.7)

0.611

Aches and pain

18 (64.3)

19 (67.9)

1.000

Leukopenia

6 (21.4)

11 (39.3)

0.611

Any warning sign

19 (67.9)

27 (96.4)

0.012

WHO 2009 criteria for warning signs

   

   Abdominal pain or tenderness

9 (32.1)

10 (35.7)

1.000

   Persistent vomiting ≥2 days

0 (0.0)

2 (7.1)

0.491

   Clinical fluid accumulation

2 (7.1)

13 (46.4)

0.002

   Mucosal bleeding

0 (0.0)

4 (14.3)

0.112

   Lethargy

11 (39.3)

16 (57.1)

0.285

   Hepatomegaly

2 (7.1)

2 (7.1)

na

   Hematocrit change ≥20%

9 (32.1)

25 (89.3)

<0.001

   Hematocrit change ≥20% with platelet <50 × 10^9/L

1 (3.6)

20 (71.4)

<0.001

   Hematocrit change ≥20% with platelet <20 × 10^9/L

1 (3.6)

14 (50.0)

<0.001

   Any warning sign

19 (67.9)

27 (96.4)

0.012

  1. na = not applicable, WHO = World Health Organization
  2. *Fisher's exact test