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Table 1 Relevant clinical and laboratory data at hospital presentation and within seven days of dengue diagnosis

From: Confirmed adult dengue deaths in Singapore: 5-year multi-center retrospective study

  No.(%) of patients
at presentation
No.(%) of patients
within seven days
of positive dengue
p*
WHO 1997 criteria for probable dengue    
   Fever/temperature ≥37.5°C plus two or more of the following: 4 (14.3) 9 (32.1) 0.205
Fever:    
Fever symptom 21 (75.0) 25 (89.3) 0.296
Temperature ≥37.5°C 19 (67.9) 25 (89.3) 0.101
Symptom/temperature ≥37.5°C 24 (85.7) 27 (96.4) 0.352
Headache 3 (10.7) 4 (14.3) 1.000
Retro-orbital pain 0 (0.0) 0 (0.0) na
Myalgia 7 (25.0) 9 (32.1) 0.768
Arthralgia 0 (0.0) 2 (7.1) 0.491
Rash 1 (3.6) 3 (10.7) 0.611
Hemorrhagic manifestation 5 (17.9) 6 (21.4) 1.000
Leukopenia 6 (21.4) 11 (39.3) 0.245
WHO 2009 criteria for probable dengue    
   Fever symptom/temperature ≥37.5°C and two of the following: 17 (60.7) 22 (78.6) 0.245
Fever symptom/temperature ≥37.5°C 24 (85.7) 27 (96.4) 0.352
Nausea or vomiting 10 (35.7) 10 (35.7) na
Rash 1 (3.6) 3 (10.7) 0.611
Aches and pain 18 (64.3) 19 (67.9) 1.000
Leukopenia 6 (21.4) 11 (39.3) 0.611
Any warning sign 19 (67.9) 27 (96.4) 0.012
WHO 2009 criteria for warning signs    
   Abdominal pain or tenderness 9 (32.1) 10 (35.7) 1.000
   Persistent vomiting ≥2 days 0 (0.0) 2 (7.1) 0.491
   Clinical fluid accumulation 2 (7.1) 13 (46.4) 0.002
   Mucosal bleeding 0 (0.0) 4 (14.3) 0.112
   Lethargy 11 (39.3) 16 (57.1) 0.285
   Hepatomegaly 2 (7.1) 2 (7.1) na
   Hematocrit change ≥20% 9 (32.1) 25 (89.3) <0.001
   Hematocrit change ≥20% with platelet <50 × 10^9/L 1 (3.6) 20 (71.4) <0.001
   Hematocrit change ≥20% with platelet <20 × 10^9/L 1 (3.6) 14 (50.0) <0.001
   Any warning sign 19 (67.9) 27 (96.4) 0.012
  1. na = not applicable, WHO = World Health Organization
  2. *Fisher's exact test