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Table 4 Comparison of inpatients and outpatients with pulmonary tuberculosis with regard to the factors associated with non-positive QuantiFERON results

From: Performance of whole-blood interferon-gamma release assay in patients admitted to the emergency department with pulmonary infiltrates

Covariates Inpatients P value Outpatients P value
  Positive QFT
(n = 51)
Non-positive QFT
(n = 37)
  Positive QFT
(n = 77)
Non-positive QFT
(n 16)
 
Laboratory findings       
   WBC, cells/μL 8566 ± 3438 10604 ± 5464 0.050 7723 ± 2372 7526 ± 2212 0.761
   Lymphocytes, cells/μL 1203 ± 509 885 ± 440 0.003 1 787 ± 642 1508 ± 504 0.105
   Lymphocytopenia* 20 (39.2) 24 (64.9) 0.018 7 (9.3) 1 (7.7) 1.0
   Albumin, g/dL 3.6 ±0.64 3.1 ± 0.59 0.003 4.4 ± 0.40 4.1 ± 0.56 0.051
   ESR, mm/hr 60.5 ± 35.15 62. 5 ± 35.97 0.806 33.9 ± 27.1 58.1 ± 33.4 0.004
   CRP, mg/dL 6.5 ± 6.21 8.3 ± 6.83 0.230 2.1 ± 2.92 0.44 ± 0.30 0.452
Radiographic extent of disease       
   Mild 19 (37.3 ) 13 (35.1 ) 0.589 55 (71.4 ) 6 (37.5) 0.020
   Moderate 19 (37.3) 11 (29.7 )   21 (27.3) 10 (62.5)  
   Advanced 13 (25.5) 13 (35.1)   1 (1.3) 0  
  1. Data are shown as mean ± SD or No. (%).
  2. WBC, white blood cells; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; QFT = QuantiFERON (performed by QuantiFERON®-TB Gold or QuantiFERON®-TB Gold In-Tube).
  3. * Lymphocytopenia; < 1,000 cells/μL.